Other Modified Nucleosides
Tetrahydrouridine
Quick view. We supply Tetrahydrouridine as a cytidine deaminase inhibitor and nucleoside analog used in biochemical and pharmacology research. CAS 18771-50-1. Catalog target purity: Specification on request.
Product profile
Tetrahydrouridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H16N2O6; molecular weight 248.23).
Tetrahydrouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For Tetrahydrouridine, reported solubility: Methanol (Slightly), Water (Slightly). Storage: -20°C.
Names and search terms
Confirmed or normalized name variants
- nsc-112907
- nsc-112907-d
- DFMA | RMI 71897
- 3,4,5,6-tetrahydrouridine
- Tetrahydrouridine dihydrate
- Uridine, 3,4,5,6-tetrahydro-
- tetrahydro-4-hydroxy-1-beta-d-ribofuranosyl-2(1h)-pyrimidinon
- (4S)-3,4,5,6-Tetrahydro-4β-hydroxy-1-(β-D-ribofuranosyl)pyrimidin-2(1H)-one
Useful catalog search terms
- CAS 18771-50-1
- Nucleoside or protected nucleoside intermediate
- Other Modified Nucleosides
Physicochemical data
| Melting point | >195°C (dec.) |
|---|---|
| Boiling point | 668.6±55.0 °C(Predicted) |
| Density | 1.622±0.06 g/cm3(Predicted) |
| pKa | 12.50±0.40(Predicted) |
| Form | Solid |
| Color | White to Off-White |
| SMILES | OC1CCN([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C(N1)=O |
| InChI | 1S/C9H16N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4-8,12-15H,1-3H2,(H,10,16)/t4-,5?,6-,7-,8-/m1/s |
| InChIKey | UCKYOOZPSJFJIZ-XVKVHKPRSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for Tetrahydrouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0156 and CAS 18771-50-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Other Modified Nucleosides product family and its named chemistry.