BX Lab

Cyclic Dinucleotides

2',2'-cGAMP

Quick view. We supply 2',2'-cGAMP as a noncanonical linkage isomer for cyclic GMP-AMP structure-activity research. CAS 1465774-27-9. Catalog target purity: ≥99%.

Structure and identity

The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.

Identifiers available

CAS, molecular formula, SMILES or InChI data are shown below when available.

Identity control

We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.

Qualification output

Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.

Catalog numberBX-CDN-0015
CAS number1465774-27-9
Purity≥99%
Pack sizeCustomized to customer requirements

Product profile

Material identity

2',2'-cGAMP is classified as cyclic dinucleotide second messenger or analog (Formula C20H24N10O13P2; molecular weight 674.41).

Typical application

2',2'-cGAMP can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.

Handling focus

For 2',2'-cGAMP, reported solubility: Aqueous solubility is salt-form and concentration dependent; confirm the current lot specification before preparing a stock. Storage: Store sealed and dry; use the lot-specific CoA for the recommended temperature and hold time.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

Key chemistry motifscyclic dinucleotide topology
Purity basisResearch-grade target; the lot-specific CoA reports the release result and analytical method.
LinkageTwo 2'-5' phosphodiester linkages
Supply formDry research material
Boiling point1159.9±75.0 °C(Predicted)
Density2.61±0.1 g/cm3(Predicted)
pKa0.88±0.70(Predicted)
FormA crystalline solid

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Additional application examples

Product-specific evaluation notes

Potential advantages

Method limitations

These points describe 2',2'-cGAMP or its named chemical feature. Broader product-family guidance is maintained on the category page.

Related products

BX-CDN-0001

2',3'-cGAMP

Cyclic Dinucleotides · CAS: 1441190-66-4

BX-CDN-0002

2',3'-cGAMP sodium salt

Cyclic Dinucleotides · CAS: 2734858-36-5

BX-CDN-0003

2'3'-c-di-AM(PS)2 (Rp,Rp) disodium salt

Cyclic Dinucleotides · CAS: 1638750-95-4

BX-CDN-0004

3',3'-cGAMP

Cyclic Dinucleotides · CAS: 849214-04-6

BX-CDN-0005

2'3'-c-di-AM(PS)2 (Rp,Rp) ammonium salt

Cyclic Dinucleotides · CAS: 1638750-96-5

BX-CDN-0006

2'3'-c-di-AM(PS)2 (Rp,Rp)

Cyclic Dinucleotides · CAS: 1638241-89-0

Frequently asked questions

Can the package size for 2',2'-cGAMP be customized?

Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.

What information should be included in a quote request?

Quote catalog number BX-CDN-0015 and CAS 1465774-27-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.

Product-family literature

The publications below provide peer-reviewed context for the Cyclic Dinucleotides product family and its named chemistry.

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