Amino-modified Nucleosides
2-Amino-2'3'-dideoxyadenosine
Quick view. We supply 2-Amino-2'3'-dideoxyadenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 107550-73-2. Catalog target purity: Specification on request.
Product profile
2-Amino-2'3'-dideoxyadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N6O2; molecular weight 250.26).
2-Amino-2'3'-dideoxyadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2-Amino-2'3'-dideoxyadenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 2,6-Diaminopurine 2',3'-dideoxyriboside
- 2-NH2-2',3'-ddA
- Adenosine, 2-aMino-2',3'-dideoxy-
- 2,6-Diamino-2',3'-dideoxypurine-9-ribofuranoside
- 2,6-Diamino-9-(2,3-dideoxy-β-D-ribofuranosyl)-9H-purine
Useful catalog search terms
- CAS 107550-73-2
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C10H14N6O2/c11-8-7-9(15-10(12)14-8)16(4-13-7)6-2-1-5(3-17)18-6/h4-6,17H,1-3H2,(H4,11,12,14,15)/t5-,6+/m0/s |
| InChIKey | OABUIHOVHQHUAO-NTSWFWBYSA-N |
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=NC3=C(N=C(N=C32)N)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2-Amino-2'3'-dideoxyadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2-Amino-2'3'-dideoxyadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0007 and CAS 107550-73-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.