Amino-modified Nucleosides
3'-NH₂-ddC
Quick view. We supply 3'-NH₂-ddC as a 3'-amino dideoxycytidine analog for chain-terminator and conjugation chemistry. CAS 84472-90-2. Catalog target purity: ≥99%.
Product profile
3'-NH₂-ddC is classified as nucleoside or protected nucleoside intermediate (Formula C9H14N4O3; molecular weight 226.23).
3'-NH₂-ddC can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-NH₂-ddC, reported solubility: DMSO (Slightly), Methanol (Slightly). Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere.
Names and search terms
Confirmed or normalized name variants
- 3'-amino-2',3'-dideoxycytidine
- Cytidine, 3'-amino-2',3'-dideoxy-
- 4-Amino-1-[4-amino-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- 4-Amino-1-((2R,4S,5S)-4-amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Useful catalog search terms
- CAS 84472-90-2
- Nucleoside or protected nucleoside intermediate
- Amino-modified Nucleosides
Physicochemical data
| Melting point | >210°C (dec.) |
|---|---|
| Boiling point | 450.2±55.0 °C(Predicted) |
| Density | 1.73±0.1 g/cm3(Predicted) |
| pKa | 14.44±0.10(Predicted) |
| Form | Solid |
| Color | White to Off-White |
| InChI | InChI=1S/C9H14N4O3/c10-5-3-8(16-6(5)4-14)13-2-1-7(11)12-9(13)15/h1-2,5-6,8,14H,3-4,10H2,(H2,11,12,15) |
| InChIKey | LDQAHTVPOZCQNH-UHFFFAOYSA-N |
| SMILES | N=c1ccn(C2CC(N)C(CO)O2)c(O)n |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 3'-NH₂-ddC or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-NH₂-ddC be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0007 and CAS 84472-90-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.