Phosphorus Reagents
2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite
Quick view. An activated P(III) reagent used to introduce a 2-cyanoethyl phosphoramidite unit into alcohol-bearing building blocks. CAS 102691-36-1. Catalog target purity: Specification on request.
Product profile
2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite is classified as protected oligonucleotide phosphoramidite building block (Formula C15H32N3OP; molecular weight 301.41).
2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite — Preparation of nucleoside phosphoramidites for solid-phase oligonucleotide synthesis.
For 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite, reported solubility: Acetonitrile (Slightly), Benzene, Chloroform (Sparingly), Methanol (Slightly). Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- 2-CYANOETHYL N,N,N',N'-TETRAISOPROPYLPHOSPHORAMIDITE
- 2-CYANOETHYL N,N,N',N'-TETRAISOPROPYLPHOSPHORDIAMIDITE
- 2-CYANOETHYL TETRAISOPROPYLPHOSPHORODIAMIDITE
- BIS(DIISOPROPYLAMINO)(2-CYANOETHOXY)PHOSPHINE
- P-REAGENT
- Phosphorodiamidous acid, tetrakis(1-methylethyl)-, 2-cyanoethyl ester
- 2-CYANOETHYL-N,N,N'',N''-TETRAISO-PROPYLPHOSPHORAMIDITE(P-REAGENT)
- b-cyanoethyl-N,N,N',N'-tetraisopropylphosphorodiamidite
Useful catalog search terms
- CAS 102691-36-1
- Protected oligonucleotide phosphoramidite building block
- phosphoramidite coupling group
- Phosphorus Reagents
Physicochemical data
| Key chemistry motifs | phosphoramidite coupling group |
|---|---|
| Density | 0.949 g/mL at 25 °C(lit.) |
| Form | liquid |
| Color | colorless |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)N(C(C)C)C(C)C |
| InChI | 1S/C15H32N3OP/c1-12(2)17(13(3)4)20(19-11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3 |
| InChIKey | RKVHNYJPIXOHRW-UHFFFAOYSA-N |
| Boiling point | 100 °C0.5 mm Hg(lit.) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Phosphitylation of protected alcohols with a 2-cyanoethyl-protected phosphorus group.
Related products
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BX-PR-0002Methylenediphosphonic acid
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BX-PR-0003Tetraethyl methylenebis(phosphonate)
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BX-PR-0004TetraPOM methylenebis(phosphonate)
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BX-PR-0005Bis(tributylammonium) pyrophosphate (50% wt in ACN)
Phosphorus Reagents · CAS: 5975-18-8
BX-PR-0006Tetramethyl methylenebis(phosphonate)
Phosphorus Reagents · CAS: 16001-93-7
Frequently asked questions
Can the package size for 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PR-0008 and CAS 102691-36-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Phosphorus Reagents product family and its named chemistry.