Phosphorus Reagents
TetraPOM methylenebis(phosphonate)
Quick view. We supply TetraPOM methylenebis(phosphonate) as a methylenebis(phosphonate) or related phosphorus reagent for phosphate-mimic and medicinal chemistry workflows. CAS 134606-34-1. Catalog target purity: Specification on request.
Product profile
TetraPOM methylenebis(phosphonate) is classified as specialty phosphorus reagent or intermediate (Formula C25H46O14P2; molecular weight 632.58).
TetraPOM methylenebis(phosphonate) — 2,2-Dimethylpropanoic Acid 1.1’,1’,1’’’-[Methylenebis[phosphinylidynebis(oxymethylene)]] Ester is a reagent used in the preparation of Vinylphosphonate-modified siRNA congugates which may be used in treatments of genetic diseases.
For TetraPOM methylenebis(phosphonate), reported solubility: Chloroform (Slightly), Ethyl Acetate (Slightly). Storage: -20°C, Inert atmosphere.
Names and search terms
Useful catalog search terms
- CAS 134606-34-1
- Specialty phosphorus reagent or intermediate
- Phosphorus Reagents
Physicochemical data
| Melting point | 68-72°C |
|---|---|
| Boiling point | 636.0±55.0 °C(Predicted) |
| Density | 1.195±0.06 g/cm3(Predicted) |
| Form | Solid |
| Color | Off-White to Pale Yellow |
| SMILES | C(P(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)P(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C |
| InChI | InChI=1S/C25H46O14P2/c1-22(2,3)18(26)32-13-36-40(30,37-14-33-19(27)23(4,5)6)17-41(31,38-15-34-20(28)24(7,8)9)39-16-35-21(29)25(10,11)12/h13-17H2,1-12H3 |
| InChIKey | UNXRGZHZKHCCJB-UHFFFAOYSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- TetraPOM methylenebis(phosphonate) can be used as a defined research input for chemistry feasibility, analytical method development and material comparison.
- Typical qualification includes identity, purity method, storage, handling and downstream workflow compatibility.
- Related analogs, impurity standards and custom quantities can be reviewed for project-specific research needs.
Related products
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BX-PR-0002Methylenediphosphonic acid
Phosphorus Reagents · CAS: 1984-15-2
BX-PR-0003Tetraethyl methylenebis(phosphonate)
Phosphorus Reagents · CAS: 1660-94-2
BX-PR-0005Bis(tributylammonium) pyrophosphate (50% wt in ACN)
Phosphorus Reagents · CAS: 5975-18-8
BX-PR-0006Tetramethyl methylenebis(phosphonate)
Phosphorus Reagents · CAS: 16001-93-7
BX-PR-0007BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE
Phosphorus Reagents · CAS: 102690-88-0
Frequently asked questions
Can the package size for TetraPOM methylenebis(phosphonate) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PR-0004 and CAS 134606-34-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.