Phosphorus Reagents
BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE
Quick view. A P(III) phosphitylating reagent bearing two 2-cyanoethoxy groups and a diisopropylamino leaving group. CAS 102690-88-0. Catalog target purity: Specification on request.
Product profile
BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE is classified as protected oligonucleotide phosphoramidite building block (Formula C12H22N3O2P; molecular weight 271.3).
BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE — Preparation of bis(2-cyanoethyl)-protected phosphate intermediates.
For BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE, reported solubility: Chloroform (Sparingly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly). Storage: -20°C Freezer, Under Inert Atmosphere.
Names and search terms
Confirmed or normalized name variants
- bis(2-cyanoethyl) diisopropylphosphoramidite
- DIISOPROPYLAMINO-DI-(2-CYANOETHOXY)-PHOSPHINE
- BIS(2-CYANOETHOXY)(DIISOPROPYLAMINO)PHOSPHINE
- BIS(2-CYANOETHOXY)-N,N-DIISOPROPYLAMINOPHOSPHINE
- Bis(2-cyanoethyl) N,N-bis(isopropyl)phosphoramidite
- REF DUPL: Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite
- BIS(1-METHYLETHYL)PHOSPHORAMIDOUS ACID BIS(2-CYANOETHYL) ESTER
- PhosphoraMidous acid,N,N-bis(1-Methylethyl)-, bis(2-cyanoethyl) ester
Useful catalog search terms
- CAS 102690-88-0
- Protected oligonucleotide phosphoramidite building block
- phosphoramidite coupling group
- Phosphorus Reagents
Physicochemical data
| Key chemistry motifs | phosphoramidite coupling group |
|---|---|
| Boiling point | 335.3±27.0 °C(Predicted) |
| Density | 1.039 g/mL at 25 °C |
| Form | liquid |
| Color | Colourless |
| SMILES | P(N(C(C)C)C(C)C)(OCCC#N)OCCC#N |
| InChI | InChI=1S/C12H22N3O2P/c1-11(2)15(12(3)4)18(16-9-5-7-13)17-10-6-8-14/h11-12H,5-6,9-10H2,1-4H3 |
| InChIKey | LDHWBEHZLFDXCU-UHFFFAOYSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Phosphitylation of alcohol-bearing building blocks in nucleotide-chemistry routes.
Related products
1,2-Bis(diethylphosphino)ethane
Phosphorus Reagents · CAS: 6411-21-8
BX-PR-0002Methylenediphosphonic acid
Phosphorus Reagents · CAS: 1984-15-2
BX-PR-0003Tetraethyl methylenebis(phosphonate)
Phosphorus Reagents · CAS: 1660-94-2
BX-PR-0004TetraPOM methylenebis(phosphonate)
Phosphorus Reagents · CAS: 134606-34-1
BX-PR-0005Bis(tributylammonium) pyrophosphate (50% wt in ACN)
Phosphorus Reagents · CAS: 5975-18-8
BX-PR-0006Tetramethyl methylenebis(phosphonate)
Phosphorus Reagents · CAS: 16001-93-7
Frequently asked questions
Can the package size for BIS(2-CYANOETHYL)-N,N-DIISOPROPYL PHOSPHORAMIDITE be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PR-0007 and CAS 102690-88-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Phosphorus Reagents product family and its named chemistry.