2'-F Nucleosides
2'-F-dI
Quick view. We supply 2'-F-dI as a 2'-fluoro nucleoside for modified nucleotide, amidite and nucleoside analog synthesis. CAS 80049-87-2. Catalog target purity: ≥98%.
Product profile
2'-F-dI is classified as nucleoside or protected nucleoside intermediate (Formula C10H11FN4O4; molecular weight 270.22).
2'-F-dI can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-F-dI, storage: Sealed in dry,Room Temperature. Form: Powder.
Names and search terms
Confirmed or normalized name variants
- 2'-deoxy-2'-fluoroinosine
- Inosine, 2'-deoxy-2'-fluoro-
- 2'-Deoxy-2'-fluoro-D-inosine
- 9-(2-Deoxy-2-fluoro-beta-D-ribofuranosyl)hypoxanthine
- 9-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol
Useful catalog search terms
- CAS 80049-87-2
- Nucleoside or protected nucleoside intermediate
- 2'-fluoro modification
- 2'-F Nucleosides
Physicochemical data
| Key chemistry motifs | 2'-fluoro modification |
|---|---|
| Form | Powder |
| Color | White to Off-white |
| InChI | InChI=1S/C10H11FN4O4/c11-5-7(17)4(1-16)19-10(5)15-3-14-6-8(15)12-2-13-9(6)18/h2-5,7,10,16-17H,1H2,(H,12,13,18)/t4-,5-,7-,10-/m1/s |
| InChIKey | NRVOTDBYJXFINS-QYYRPYCUSA-N |
| SMILES | OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)[C@H](F)[C@@H]1O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-F-dI or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2'-F-dA
2'-F Nucleosides · CAS: 64183-27-3
BX-MN-01812'-F-dU
2'-F Nucleosides · CAS: 784-71-4
BX-MN-01822'-F-dC
2'-F Nucleosides · CAS: 10212-20-1
BX-MN-01832'-F-dG
2'-F Nucleosides · CAS: 78842-13-4
BX-2FN-00034'-Azido-2'-deoxy-2'-fluoroaracytidine
2'-F Nucleosides · CAS: 1011529-10-4
BX-2FN-00045'-Azido-2',5'-dideoxy-2'-fluorouridine
2'-F Nucleosides · CAS: 1012080-88-4
Frequently asked questions
Can the package size for 2'-F-dI be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FN-0001 and CAS 80049-87-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the 2'-F Nucleosides product family and its named chemistry.