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BX LAB PRODUCT CATEGORY

Linker Phosphoramidites

Quick view. Spacer, amino, thiol, phosphorylation and other linker phosphoramidites for oligonucleotide conjugation. This category currently includes 26 products. Linker Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

Products26
Use scopeResearch use only
Pack sizeCustomized to requirements
SupportSelection and custom synthesis review

Category guide

Typical use

Linker Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

How to select

Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.

How to qualify

Review identity, chromatographic purity, phosphorus-related quality attributes, water sensitivity and performance in a short test sequence.

Product-family considerations

Common advantages
  • Phosphoramidite chemistry is modular, automated and compatible with fast sequence iteration.
  • Modified sugar, base or linker motifs let researchers tune duplex stability, specificity, hydrophobicity, steric profile and downstream conjugation options.
Common limitations
  • Modified amidites can require adjusted coupling time, activator choice, deprotection conditions and analytical release methods.
  • Moisture sensitivity and storage history are important because degraded amidite can reduce coupling efficiency.

Category literature

These publications provide background for the Linker Phosphoramidites product family. Individual product pages only show additional product- or feature-relevant references.

Selection checklist

Exact identityMatch the canonical name with a CAS number, structure, SMILES or drawing; confirm stereochemistry, protecting groups and salt form where applicable.
SpecificationDefine target purity, analytical method, water or residual-solvent concerns and any application-specific acceptance limits.
Workflow fitShare the reaction, enzyme, sequence, solvent system, support or analytical method used to evaluate compatibility.
Supply needProvide initial quantity, expected future scale, packaging preference, timeline and documentation requirements.

26 products

Chemical structure of Thiol-Modifier C6 S-S CE PhosphoramiditeThiol-Modifier C6 S-S CE Phosphoramidite

≥98% · CAS: 148254-21-1

BX-LP-0016
Chemical structure of 2-O-DMTr-Sulfonyldiethanol-CE-Phosphoramidite2-O-DMTr-Sulfonyldiethanol-CE-Phosphoramidite

≥98% · CAS: 108783-02-4

BX-LP-0010
Chemical structure of 5'-Amino-Modifier C6-TFA CE Phosphoramidite5'-Amino-Modifier C6-TFA CE Phosphoramidite

≥98% · CAS: 133975-85-6

BX-LP-0011
Chemical structure of 6-palmitamidohexyl CE Phosphoramidite6-palmitamidohexyl CE Phosphoramidite

≥98% · CAS: 1772522-18-5

BX-LP-0012
Chemical structure of Spacer C12 PhosphoramiditeSpacer C12 Phosphoramidite

≥98% · CAS: 158665-27-1

BX-LP-0013
Chemical structure of Spacer 9 PhosphoramiditeSpacer 9 Phosphoramidite

≥98% · CAS: 146668-73-7

BX-LP-0025
Chemical structure of Spacer 18 PhosphoramiditeSpacer 18 Phosphoramidite

≥98% · CAS: 125607-09-2

BX-LP-0026
Chemical structure of Chemical Phosphorylation Reagent IIChemical Phosphorylation Reagent II

≥98% · CAS: 171285-25-9

BX-LP-0028
Chemical structure of Solid Chemical Phosphorylation Reagent IISolid Chemical Phosphorylation Reagent II

≥98% · CAS: 202284-84-2

BX-LP-0029
Chemical structure of MMTr-C12 Amino-Linker PhosphoramiditeMMTr-C12 Amino-Linker Phosphoramidite

≥98% · CAS: 178925-51-4

BX-LP-0031
Chemical structure of MMTr-C6 Amino-Linker PhosphoramiditeMMTr-C6 Amino-Linker Phosphoramidite

≥98% · CAS: 114616-27-2

BX-LP-0033
Chemical structure of 5'-Hexynyl Phosphoramidite5'-Hexynyl Phosphoramidite

≥98% · CAS: 1048985-37-0

BX-LP-0015
Chemical structure of 5'-DBCO-TEG Phosphoramidite5'-DBCO-TEG Phosphoramidite

≥98% · CAS: 1527468-08-1

BX-LP-0034
Chemical structure of Spacer C3 PhosphoramiditeSpacer C3 Phosphoramidite

≥98% · CAS: 110894-23-0

BX-LP-0023
Chemical structure of Spacer C6 PhosphoramiditeSpacer C6 Phosphoramidite

≥98% · CAS: 158041-82-8

BX-LP-0024
Chemical structure of Cholesteryl-TEG PhosphoramiditeCholesteryl-TEG Phosphoramidite

≥98% · CAS: 873435-29-1

BX-LP-0035
Chemical structure of 5'-Cholesteryl-TEG Phosphoramidite5'-Cholesteryl-TEG Phosphoramidite

≥98% · CAS: 1325147-19-0

BX-LP-0036
Chemical structure of 5'-Maleimide-Modifier Phosphoramidite5'-Maleimide-Modifier Phosphoramidite

≥98% · CAS: 1316303-83-9

BX-LP-0039
Chemical structure of Spacer PEG-N3 PhosphoramiditeSpacer PEG-N3 Phosphoramidite

≥98% · CAS: N/A

BX-LP-0014
Chemical structure of standard-orientation dSpacer CE phosphoramiditeAbasic Phosphoramidite

≥98% · CAS: 129821-76-7

BX-RP-0009
Chemical structure of Spacer C2 PhosphoramiditeSpacer C2 Phosphoramidite

≥98% · CAS: 161029-24-9

BX-LP-0022
Chemical structure of Alpha-Tocopherol-TEG PhosphoramiditeAlpha-Tocopherol-TEG Phosphoramidite

≥98% · CAS: 1621330-39-9

BX-LP-0037
Chemical structure of 5'-Thiol-Modifier C65'-Thiol-Modifier C6

≥98% · CAS: 116919-17-6

BX-LP-0038
Chemical structure of DBCO-Serinol PhosphoramiditeDBCO-Serinol Phosphoramidite

≥98% · CAS: N/A

BX-LP-0064
Chemical structure of DBCO-dT-CE PhosphoramiditeDBCO-dT-CE Phosphoramidite

≥98% · CAS: N/A

BX-LP-0065
Chemical structure of Dithiol Serinol PhosphoramiditeDithiol Serinol Phosphoramidite

≥98% · CAS: N/A

BX-LP-0069

Frequently asked questions

What are typical uses for Linker Phosphoramidites?

Linker Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

What should be confirmed before ordering Linker Phosphoramidites?

Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.

Are custom quantities or related analogs available?

BX Lab reviews custom package sizes, catalog-adjacent analogs and research-use custom synthesis requests against the target structure, purity, scale and timeline.

Need help selecting a product?

Tell our scientists about your target chemistry, workflow, required purity and scale. We can help identify a catalog product, related analog or custom route.

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