Modified Nucleosides
2',3'-Dideoxy-2',3'-didehydroadenosine
Quick view. We supply 2',3'-Dideoxy-2',3'-didehydroadenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 7057-48-9. Catalog target purity: Specification on request.
Product profile
2',3'-Dideoxy-2',3'-didehydroadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H11N5O2; molecular weight 233.23).
2',3'-Dideoxy-2',3'-didehydroadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2',3'-Dideoxy-2',3'-didehydroadenosine, reported solubility: Soluble in DMSO. Storage: 2-8°C(protect from light).
Names and search terms
Confirmed or normalized name variants
- D4A
- NSC 108602
- BETA-L-D4A
- Compound FL0097
- Didanosin EP Imp I
- Didanosine EP Impurity I
- 2',3'-Dideoxy-2'3'-didehy...
- 2'3'-didehydro-2'3'-dideoxyadenosine
Useful catalog search terms
- CAS 7057-48-9
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H11N5O2/c11-9-8-10(13-4-12-9)15(5-14-8)7-2-1-6(3-16)17-7/h1-2,4-7,16H,3H2,(H2,11,12,13)/t6-,7+/m0/s |
|---|---|
| InChIKey | JFUOUIPRAAGUGF-NKWVEPMBSA-N |
| SMILES | C1=C[C@@H](O[C@@H]1CO)N2C=NC3=C2N=CN=C3N |
| Melting point | 187-189°C |
| Boiling point | 553.9±60.0 °C(Predicted) |
| Density | 1.74±0.1 g/cm3(Predicted) |
| pKa | 14.28±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-Dideoxy-2',3'-didehydroadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-Dideoxy-2',3'-didehydroadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0651 and CAS 7057-48-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.