Base-protected Nucleosides
2',3'-dideoxy-C(Ac)
Quick view. We supply 2',3'-dideoxy-C(Ac) as a protected dideoxy nucleoside intermediate for chain-terminator, analog and modified nucleotide synthesis. CAS 119818-52-9. Catalog target purity: ≥98%.
Product profile
2',3'-dideoxy-C(Ac) is classified as nucleoside or protected nucleoside intermediate (Formula C11H15N3O4; molecular weight 253.26 g/mol (calculated from molecular formula)).
2',3'-dideoxy-C(Ac) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2',3'-dideoxy-C(Ac), polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- Acetamide, N-[1,2-dihydro-2-oxo-1-[tetrahydro-5-(hydroxymethyl)-2-furanyl]-4-pyrimidinyl]-, (2R-cis)-
Useful catalog search terms
- CAS 119818-52-9
- Nucleoside or protected nucleoside intermediate
- Base-protected Nucleosides
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-dideoxy-C(Ac) or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-dideoxy-C(Ac) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0002 and CAS 119818-52-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Base-protected Nucleosides product family and its named chemistry.