Modified Nucleosides
2'-Deoxy-2',2'-difluro cytidine
Quick view. We supply 2'-Deoxy-2',2'-difluro cytidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 95058-81-4. Catalog target purity: Specification on request.
Product profile
2'-Deoxy-2',2'-difluro cytidine is classified as nucleoside or protected nucleoside intermediate (Formula C9H11F2N3O4; molecular weight 263.2).
2'-Deoxy-2',2'-difluro cytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-Deoxy-2',2'-difluro cytidine, reported solubility: Methanol (Slightly), Water (Slightly, Heated). Storage: Keep in dark place,Sealed in dry,Store in freezer, under -20°C.
Names and search terms
Confirmed or normalized name variants
- gemcitabine
- 2'-DEOXY-2',2'-DIFLUOROCYTIDINE
- 4-amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- GEMCITABINE HCL USP
- 2'-Deoxy-2',2'-difluro cytidine Hydrochloride
- 2'-Deoxy-2',2'-difluoro-D-cytidine
- 2''-DEOXY-2'',2''-DIFLUOROCYTIDINE(GEMCITABINE)
- 2',2'-Difluorodeoxycytidine
Useful catalog search terms
- CAS 95058-81-4
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C9H11F2N3O4/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17)/t4-,6-,7-/m1/s |
|---|---|
| InChIKey | SDUQYLNIPVEERB-QPPQHZFASA-N |
| SMILES | OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@](F)(F)[C@@H]1O |
| Melting point | 168,64 C |
| Boiling point | 482.7±55.0 °C(Predicted) |
| Density | 1.84±0.1 g/cm3(Predicted) |
| pKa | 11.65±0.70(Predicted) |
| Form | Solid |
| Color | White to Off-White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
(S)-cEt-rA
Modified Nucleosides · CAS: 1197033-34-3
BX-OP-0069S-Adenosylmethionine (SAM)
Modified Nucleosides · CAS: 485-80-3
BX-MN-0185(R-/S-) 5-Carbamoylhydroxy methyluridine
Modified Nucleosides · CAS: N/A
BX-MN-0186(R-/S-)5-(1-Hydroxy)(methoxycarbonyl)methyl uridine
Modified Nucleosides · CAS: N/A
BX-MN-0187(R-/S-)5-Carboxyhydroxymethyl uridine
Modified Nucleosides · CAS: N/A
BX-MN-0719(R)-N-(2,3-dihydro-1H-indenyl)adenosine
Modified Nucleosides · CAS: 96392-15-3
Frequently asked questions
Can the package size for 2'-Deoxy-2',2'-difluro cytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0715 and CAS 95058-81-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.