Modified Nucleosides
2'-Deoxy-4-thiouridine
Quick view. We supply 2'-Deoxy-4-thiouridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 5580-20-1. Catalog target purity: Specification on request.
Product profile
2'-Deoxy-4-thiouridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H12N2O4S; molecular weight 244.27).
2'-Deoxy-4-thiouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-Deoxy-4-thiouridine, storage: -20°C. Form: Solid.
Names and search terms
Confirmed or normalized name variants
- 1-(2-Deoxypentofuranosyl)-4-sulfanylpyrimidin-2(1H)-one
- 4-Thiodeoxyuridine
- Uridine, 2'-deoxy-4-thio-
Useful catalog search terms
- CAS 5580-20-1
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C9H12N2O4S/c12-4-6-5(13)3-8(15-6)11-2-1-7(16)10-9(11)14/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,16) |
|---|---|
| InChIKey | PHNDUXLWAVSUAL-UHFFFAOYSA-N |
| SMILES | O=c1nc(S)ccn1C1CC(O)C(CO)O1 |
| Form | Solid |
| Color | Light yellow to yellow |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2'-Deoxy-4-thiouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0584 and CAS 5580-20-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.
