Amino-modified Nucleosides
2-NH₂-rA
Quick view. We supply 2-NH₂-rA as 2-aminoadenosine, a purine analog used in nucleoside SAR and modified RNA research. CAS 2096-10-8. Catalog target purity: Specification on request.
Product profile
2-NH₂-rA is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N6O4; molecular weight 282.26).
2-NH₂-rA can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2-NH₂-rA, reported solubility: Aqueous Acid (Slightly, Heated, Sonicated), DMSO (Slightly, Sonicated), Ethanol. Storage: Keep in dark place,Sealed in dry,Room Temperature.
Names and search terms
Confirmed or normalized name variants
- 2,6-DIAMINOPURINE RIBOSIDE
- 2-AMINE ADENOSINE
- 2-AMINOADENOSINE
- (2R,3R,4S,5R)-2-(2,6-Diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Useful catalog search terms
- CAS 2096-10-8
- Nucleoside or protected nucleoside intermediate
- Amino-modified Nucleosides
Physicochemical data
| Melting point | 241-243°C (dec.) |
|---|---|
| Boiling point | 798.5±70.0 °C(Predicted) |
| Density | 2.25±0.1 g/cm3(Predicted) |
| pKa | 13.10±0.70(Predicted) |
| Form | Powder |
| Color | White to Off-White |
| SMILES | OC[C@H]1O[C@@H](N2C3C(=C(N=C(N)N=3)N)N=C2)[C@H](O)[C@@H]1O |
| InChI | InChI=1S/C10H14N6O4/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H4,11,12,14,15)/t3-,5-,6-,9-/m1/s |
| InChIKey | ZDTFMPXQUSBYRL-UUOKFMHZSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2-NH₂-rA or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2-NH₂-rA be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0176 and CAS 2096-10-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.