Modified Nucleosides
2-Thiothymidine
Quick view. We supply 2-Thiothymidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 28585-51-5. Catalog target purity: Specification on request.
Product profile
2-Thiothymidine is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N2O4S; molecular weight 258.29).
2-Thiothymidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2-Thiothymidine, form: Solid.
Names and search terms
Confirmed or normalized name variants
- 2-Thio-2'-deoxythymidine
- Thymidine, 2-thio-
- 2'-deoxy-5-methyl-2-thiouridine
- 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
Useful catalog search terms
- CAS 28585-51-5
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H14N2O4S/c1-5-3-12(10(17)11-9(5)15)8-2-6(14)7(4-13)16-8/h,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s |
|---|---|
| InChIKey | PISWNSOQFZRVJK-XLPZGREQSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=S)C[C@@H]1O |
| Form | Solid |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2-Thiothymidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0432 and CAS 28585-51-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.