Halogenated Nucleosides
5'-deoxy-5-fluorouridine
Quick view. We supply 5'-deoxy-5-fluorouridine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 3094-09-5. Catalog target purity: Specification on request.
Product profile
5'-deoxy-5-fluorouridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H11FN2O5; molecular weight 246.19).
5'-deoxy-5-fluorouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-deoxy-5-fluorouridine, reported solubility: DMSO (Slightly), Methanol (Slightly). Storage: Inert atmosphere,Room Temperature.
Names and search terms
Confirmed or normalized name variants
- doxifluridine
- 5'-DEOXYFLUOROURIDINE
- 5'-DFUR
- 5'DFURD
- (+)-5-FLUORO-5'-DEOXYURIDINE
- RO-21-9738
- 5’-deoxy-5-fluoro-uridin
- flutron
Useful catalog search terms
- CAS 3094-09-5
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C9H11FN2O5/c1-3-5(13)6(14)8(17-3)12-2-4(10)7(15)11-9(12)16/h2-3,5-6,8,13-14H,1H3,(H,11,15,16)/t3-,5-,6-,8-/m1/s |
|---|---|
| InChIKey | ZWAOHEXOSAUJHY-ZIYNGMLESA-N |
| SMILES | C[C@H]1O[C@@H](N2C=C(F)C(=O)NC2=O)[C@H](O)[C@@H]1O |
| Melting point | 188-192 °C(lit.) |
| Density | 1.3751 (estimate) |
| pKa | 7.4(at 25℃) |
| Form | Solid |
| Color | White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 5'-deoxy-5-fluorouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-deoxy-5-fluorouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0222 and CAS 3094-09-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.