Halogenated Nucleosides
5-Iodo-2'-deoxyuridine
Quick view. We supply 5-Iodo-2'-deoxyuridine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 54-42-2. Catalog target purity: Specification on request.
Product profile
5-Iodo-2'-deoxyuridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H11IN2O5; molecular weight 354.1).
5-Iodo-2'-deoxyuridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5-Iodo-2'-deoxyuridine, reported solubility: DMSO (Slightly, Sonicated), Methanol (Slightly, Heated, Sonicated). Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- idoxuridine
- 1-(2-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODOURACIL
- 2'-DEOXY-5-IODOURIDINE
- 5-IODO-2'-DEOXY-D-URIDINE
- 5-IODODEOXYURIDINE
- 5-IODODESOXYURIDINE
- DENDRID
- EMANIL
Useful catalog search terms
- CAS 54-42-2
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | 1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s |
|---|---|
| InChIKey | XQFRJNBWHJMXHO-FSDSQADBSA-N |
| SMILES | OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(I)C(=O)NC2=O |
| Melting point | 194 °C (lit.) |
| Density | 1.7911 (estimate) |
| pKa | 8.25(at 25℃) |
| Form | Crystalline Powder |
| Color | White to slightly beige |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5-Iodo-2'-deoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0122 and CAS 54-42-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.