Modified Nucleosides
5-methyluridine
Quick view. We supply 5-methyluridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 1463-10-1. Catalog target purity: Specification on request.
Product profile
5-methyluridine is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N2O6; molecular weight 258.23).
5-methyluridine — A primary degradation product of tRNA,
For 5-methyluridine, reported solubility: Methanol (Slightly, Heated, Sonicated), Water (Sparingly, Sonicated). Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- thymine riboside
- 1-(BETA-D-RIBOFURANOSYL)THYMIDINE
- 1-(BETA-D-RIBOFURANOSYL)THYMINE
- 5-METHYL-1-BETA-D-RIBOFURANOSYL URACIL
- 5-METHYL-D-URIDINE
- BETA-D-THYMINE RIBOSIDE
- BETA-RIBOFURANOSIDE
- ribosylthymine
Useful catalog search terms
- CAS 1463-10-1
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s |
|---|---|
| InChIKey | DWRXFEITVBNRMK-JXOAFFINSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)[C@H](O)[C@@H]1O |
| Melting point | 183-184 °C(lit.) |
| Density | 1.576±0.06 g/cm3(Predicted) |
| pKa | 9.55±0.10(Predicted) |
| Form | powder |
| Color | white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5-methyluridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
(S)-cEt-rA
Modified Nucleosides · CAS: 1197033-34-3
BX-OP-0069S-Adenosylmethionine (SAM)
Modified Nucleosides · CAS: 485-80-3
BX-MN-0185(R-/S-) 5-Carbamoylhydroxy methyluridine
Modified Nucleosides · CAS: N/A
BX-MN-0186(R-/S-)5-(1-Hydroxy)(methoxycarbonyl)methyl uridine
Modified Nucleosides · CAS: N/A
BX-MN-0187(R-/S-)5-Carboxyhydroxymethyl uridine
Modified Nucleosides · CAS: N/A
BX-MN-0719(R)-N-(2,3-dihydro-1H-indenyl)adenosine
Modified Nucleosides · CAS: 96392-15-3
Frequently asked questions
Can the package size for 5-methyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0253 and CAS 1463-10-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.