Protected Nucleosides
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyadenosine
Quick view. We supply 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyadenosine as a protected nucleoside intermediate for DNA/RNA analog synthesis and medicinal chemistry workflows. CAS 17331-22-5. Catalog target purity: Specification on request.
Product profile
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C31H31N5O5; molecular weight 553.61).
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyadenosine, storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- ST055622
- DMT-DA
- DMT-2'-dA
- 5'-DMT-2'-dA
- 2'-Deoxy-5'-O-DMT-adenosine
- 5'-O-(4 4'-DIMETHOXYTRITYL)-2'- &
- Adenosine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-deoxy-
- 5-(6-AMINOPURIN-9-YL)-2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}OXOLAN-3-OL
Useful catalog search terms
- CAS 17331-22-5
- Nucleoside or protected nucleoside intermediate
- Protected Nucleosides
Physicochemical data
| InChI | InChI=1S/C31H31N5O5/c1-38-23-12-8-21(9-13-23)31(20-6-4-3-5-7-20,22-10-14-24(39-2)15-11-22)40-17-26-25(37)16-27(41-26)36-19-35-28-29(32)33-18-34-30(28)36/h3-15,18-19,25-27,37H,16-17H2,1-2H3,(H2,32,33,34) |
|---|---|
| InChIKey | HOVSZVKDFBLXOB-UHFFFAOYSA-N |
| SMILES | COc1ccc(C(OCC2OC(n3cnc4c(N)ncnc43)CC2O)(c2ccccc2)c2ccc(OC)cc2)cc |
| Melting point | 97-98 °C(Solv: chloroform (67-66-3); ligroine (8032-32-4)) |
| Boiling point | 785.1±70.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| pKa | 13.75±0.60(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0174 and CAS 17331-22-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry.