2'-F Nucleosides
5'-O-DMT-2'-fluoro-2'-deoxyinosine
Quick view. A 5'-O-DMT-protected 2'-fluoro-2'-deoxyinosine, CAS 1951424-83-1. CAS 1951424-83-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-O-DMT-2'-fluoro-2'-deoxyinosine is classified as 2'-f nucleosides (Formula C31H29FN4O6; molecular weight 572.59).
5'-O-DMT-2'-fluoro-2'-deoxyinosine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 5'-O-DMT-2'-fluoro-2'-deoxyinosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-
- DMT-2'-F-dI
- D6-005
- MFCD22200632
- CB44012681
Useful catalog search terms
- CAS 1951424-83-1
- C31H29FN4O6
- QDCBEGXXNGZTON-QNYAKKFESA-N
Physicochemical data
| Nucleobase | Hypoxanthine |
|---|---|
| 5' protection | 5'-O-DMT |
| Sugar modification | 2'-Fluoro-2'-deoxy |
| Free hydroxyl | 3'-OH |
| Stereochemistry | Four assigned R stereocenters |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 5'-O-DMT-2'-fluoro-2'-deoxyinosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-O-DMT-2'-fluoro-2'-deoxyinosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FN-0061 and CAS 1951424-83-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-F Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.