Modified Nucleosides
5'-O-Triphenylmethyl-2'-deoxyuridine
Quick view. We supply 5'-O-Triphenylmethyl-2'-deoxyuridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 14270-73-6. Catalog target purity: Specification on request.
Product profile
5'-O-Triphenylmethyl-2'-deoxyuridine is classified as nucleoside or protected nucleoside intermediate (Formula C28H26N2O5; molecular weight 470.52).
5'-O-Triphenylmethyl-2'-deoxyuridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-Triphenylmethyl-2'-deoxyuridine, storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- 2'-Deoxy-5'-O-(triphenylmethyl)uridine
- Trt-dU
- NSC 375393
- 5'-O-Trt-2'-dU
- 5'-Trt-2'-deoxyuridine
- 5'-O-Trt-2'-deoxyuridine
- 5'-O-Trityl-2'-deoxyuridin
- 5'-O-Trityl-2'-deoxyuridine
Useful catalog search terms
- CAS 14270-73-6
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C28H26N2O5/c31-23-18-26(30-17-16-25(32)29-27(30)33)35-24(23)19-34-28(20-10-4-1-5-11-20,21-12-6-2-7-13-21)22-14-8-3-9-15-22/h1-17,23-24,26,31H,18-19H2,(H,29,32,33)/t23-,24+,26+/m0/s |
|---|---|
| InChIKey | JJJNFNLUKYZAKI-BFLUCZKCSA-N |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)O |
| Melting point | 204-205 °C |
| Density | 1.300±0.06 g/cm3(Predicted) |
| pKa | 9.39±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5'-O-Triphenylmethyl-2'-deoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0246 and CAS 14270-73-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.