GalNAc
(6R)-FR054
Quick view. We supply (6R)-FR054 as a GalNAc-related chiral intermediate for preparing liver-targeted oligonucleotide conjugates and carbohydrate-linker building blocks. CAS 10378-06-0. Catalog target purity: ≥95%.
Product profile
(6R)-FR054 is classified as galnac ligand, linker or conjugation intermediate (Formula C14H19NO8; molecular weight 329.3).
(6R)-FR054 can be evaluated in ligand, linker and conjugation-route development for oligonucleotide delivery research.
For (6R)-FR054, in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Confirmed or normalized name variants
- FR054
- 3',4',6'-Triacetate 2'-Deoxy-2-methyl-4,5-D-galactopyrano-Δ2-oxazoline
Useful catalog search terms
- CAS 10378-06-0
- GalNAc ligand, linker or conjugation intermediate
- GalNAc ligand motif
- GalNAc
Physicochemical data
| Key chemistry motifs | GalNAc ligand motif |
|---|---|
| Boiling point | 416.7±45.0 °C(Predicted) |
| Density | 1.45±0.1 g/cm3(Predicted) |
| pKa | 3.69±0.70(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical studies compare linker length, valency, attachment chemistry, purification strategy and analytical identity.
- The material may also support conjugate-reference or impurity-standard preparation.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe (6R)-FR054 or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for (6R)-FR054 be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GALN-0001 and CAS 10378-06-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the GalNAc product family and its named chemistry.