GalNAc
GalNAc-L96-tert-butyl ester
Quick view. We supply GalNAc-L96-tert-butyl ester as a protected ester intermediate for synthesizing GalNAc-L96 acids, succinates and phosphoramidites. CAS 175724-30-8. Catalog target purity: ≥95%.
Product profile
GalNAc-L96-tert-butyl ester is classified as galnac ligand, linker or conjugation intermediate (Formula C25H47NO9; molecular weight 505.64).
GalNAc-L96-tert-butyl ester can be evaluated in ligand, linker and conjugation-route development for oligonucleotide delivery research.
For GalNAc-L96-tert-butyl ester, reported solubility: Acetonitrile (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly). Storage: Refrigerator.
Names and search terms
Confirmed or normalized name variants
- Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
- Di-tert-butyl 3,3'-[{2-amino-2-[(3-tert-butoxy-3-oxopropoxy)methyl]propane-1,3-diyl}bis(oxy)]dipropanoate
Useful catalog search terms
- CAS 175724-30-8
- GalNAc ligand, linker or conjugation intermediate
- GalNAc ligand motif
- GalNAc
Physicochemical data
| Key chemistry motifs | GalNAc ligand motif |
|---|---|
| Boiling point | 543.0±50.0 °C(Predicted) |
| Density | 1.065±0.06 g/cm3(Predicted) |
| pKa | 7.30±0.10(Predicted) |
| Form | Oil |
| Color | Colourless |
| SMILES | C(OCCC(OC(C)(C)C)=O)C(N)(COCCC(OC(C)(C)C)=O)COCCC(OC(C)(C)C)=O |
| InChI | InChI=1S/C25H47NO9/c1-22(2,3)33-19(27)10-13-30-16-25(26,17-31-14-11-20(28)34-23(4,5)6)18-32-15-12-21(29)35-24(7,8)9/h10-18,26H2,1-9H3 |
| InChIKey | KPXODPHVWBQJEG-UHFFFAOYSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate is used in the preparation of dendronized polymers. Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine can be used in the synthesis of optica lly degradable dendrons for temporary adhesion of proteins to DNA. It is also used in the preparation of tricylic polyamide receptor for carbohydrate recognition.
- Typical studies compare linker length, valency, attachment chemistry, purification strategy and analytical identity.
- The material may also support conjugate-reference or impurity-standard preparation.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe GalNAc-L96-tert-butyl ester or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
(6R)-FR054
GalNAc · CAS: 10378-06-0
BX-GALN-0002AdemA-GalNAc Phosphoramidite
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BX-GALN-0003AdemC-GalNAc Phosphoramidite
GalNAc · CAS: N/A
BX-GALN-0004GalNAc PEG Cluster Phosphoramidite
GalNAc · CAS: N/A
BX-GALN-0005GalNAc-L96 Linker-Acid
GalNAc · CAS: 1426159-34-3
BX-GALN-0006GalNAc-L96 Linker-Azide
GalNAc · CAS: 2135330-72-0
Frequently asked questions
Can the package size for GalNAc-L96-tert-butyl ester be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GALN-0007 and CAS 175724-30-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the GalNAc product family and its named chemistry.