Amino-modified Nucleosides
8-Methyaminoadenosine
Quick view. We supply 8-Methyaminoadenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 13389-13-4. Catalog target purity: Specification on request.
Product profile
8-Methyaminoadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C11H16N6O4; molecular weight 296.29 g/mol (calculated from molecular formula)).
8-Methyaminoadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 8-Methyaminoadenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- N⁸-Methyl-9-pentofuranosyl-9H-purine-6,8-diamine
Useful catalog search terms
- CAS 13389-13-4
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C11H16N6O4/c1-13-11-16-5-8(12)14-3-15-9(5)17(11)10-7(20)6(19)4(2-18)21-10/h3-4,6-7,10,18-20H,2H2,1H3,(H,13,16)(H2,12,14,15) |
| InChIKey | ISWTXTWJONWIEN-UHFFFAOYSA-N |
| SMILES | CN=c1[nH]c2c(N)ncnc2n1C1OC(CO)C(O)C1O |
| Boiling point | 679.0±65.0 °C(Predicted) |
| Density | 2.00±0.1 g/cm3(Predicted) |
| pKa | 13.10±0.70(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 8-Methyaminoadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 8-Methyaminoadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0019 and CAS 13389-13-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.