Modified Nucleosides
8-Methylthio-adenosine
Quick view. We supply 8-Methylthio-adenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 29836-01-9. Catalog target purity: Specification on request.
Product profile
8-Methylthio-adenosine is classified as nucleoside or protected nucleoside intermediate (Formula C11H15N5O4S; molecular weight 313.33).
8-Methylthio-adenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 8-Methylthio-adenosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 8-(Methylsulfanyl)-9-pentofuranosyl-9H-purin-6-amine
- Adenosine,8-(methylthio)- (7CI,8CI,9CI)
Useful catalog search terms
- CAS 29836-01-9
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C11H15N5O4S/c1-21-11-15-5-8(12)13-3-14-9(5)16(11)10-7(19)6(18)4(2-17)20-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,13,14) |
|---|---|
| InChIKey | ZLSIRPOPTWVEOT-UHFFFAOYSA-N |
| SMILES | CSc1nc2c(N)ncnc2n1C1OC(CO)C(O)C1O |
| Melting point | 235-237 °C |
| Boiling point | 704.4±70.0 °C(Predicted) |
| Density | 1.98±0.1 g/cm3(Predicted) |
| pKa | 12.99±0.70(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 8-Methylthio-adenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0435 and CAS 29836-01-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.