Modified Nucleosides
8-Methylthio-guanosine
Quick view. We supply 8-Methylthio-guanosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 2104-66-7. Catalog target purity: Specification on request.
Product profile
8-Methylthio-guanosine is classified as nucleoside or protected nucleoside intermediate (Formula C11H15N5O5S; molecular weight 329.33).
8-Methylthio-guanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 8-Methylthio-guanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 4-(4-Chloroanilino)-4-oxobutanoic acid
- Guanosine, 8-(methylthio)-
Useful catalog search terms
- CAS 2104-66-7
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H10ClNO3/c11-7-1-3-8(4-2-7)12-9(13)5-6-10(14)15/h1-4H,5-6H2,(H,12,13)(H,14,15) |
|---|---|
| InChIKey | UPSNSRKMOHOEEO-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1NC(=O)CCC(=O)O)Cl |
| Density | 2.12±0.1 g/cm3(Predicted) |
| pKa | 9.17±0.20(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 8-Methylthio-guanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0367 and CAS 2104-66-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.