RNA (2'-O-TBDMS) Phosphoramidites
DMTr-2'-O-TBDMS-rU-3'-CE-Phosphoramidite
Quick view. We supply DMTr-2'-O-TBDMS-rU-3'-CE-Phosphoramidite as the routine uridine monomer for TBDMS RNA synthesis. CAS 118362-03-1. Catalog target purity: Specification on request.
Product profile
DMTr-2'-O-TBDMS-rU-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C45H61N4O9PSi; molecular weight 861.05).
DMTr-2'-O-TBDMS-rU-3'-CE-Phosphoramidite — DMT-2′O-TBDMS-rU Phosphoramidite was used in study of efficient enzyme-free copying of all four nucleobases templated by immobilized RNA.
For DMTr-2'-O-TBDMS-rU-3'-CE-Phosphoramidite, storage: Sealed in dry,2-8°C. Form: powder.
Names and search terms
Confirmed or normalized name variants
- 2'-TBDMS-U CEP
- rU Phosphoramidite
- 2’-TBDMS-rU Phosphoramidite
- 5'-O-DMT-2'-TBDMS-rU-3'-CEDPA
- 2'-TBDMS-rU-CE-Phosphoramidite
- DMT-2′O-TBDMS-rU Phosphoramidite
- 5'-DMT-2'-TBDMS-rU Phosphoramidite
- 5'-DMT-2'-O-TBDMS-Uridine Phosphoramidite
Useful catalog search terms
- CAS 118362-03-1
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- TBDMS protection
- phosphoramidite coupling group
- 2'-O-TBDMS-rU Phosphoramidite
- BX-R2OT-0013
- RNA (2'-O-TBDMS) Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; TBDMS protection; phosphoramidite coupling group |
|---|---|
| Form | powder |
| Color | white to off-white |
| SMILES | O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](O[Si](C(C)(C)C)(C)C)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,36,45,r| |
| InChIKey | SKNLXHRBXYGJOC-ZMHKPELYSA-N |
| InChI | InChI=1S/C45H61N4O9PSi/c1-31(2)49(32(3)4)59(55-29-15-27-46)57-40-38(56-42(48-28-26-39(50)47-43(48)51)41(40)58-60(10,11)44(5,6)7)30-54-45(33-16-13-12-14-17-33,34-18-22-36(52-8)23-19-34)35-20-24-37(53-9)25-21-35/h12-14,16-26,28,31-32,38,40-42H,15,29-30H2,1-11H3,(H,47,50,51)/t38-,40-,41-,42-,59?/m1/s |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- DMTr-2'-O-TBDMS-rU-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
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Frequently asked questions
Can the package size for DMTr-2'-O-TBDMS-rU-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-R2OT-0022 and CAS 118362-03-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry.