BX LAB PRODUCT CATEGORY
RNA (2'-O-TBDMS) Phosphoramidites
Quick view. 2′-O-TBDMS-protected ribonucleoside phosphoramidites for solid-phase RNA synthesis. This category currently includes 19 products. RNA (2'-O-TBDMS) Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.
Category guide
RNA (2'-O-TBDMS) Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.
Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.
Review identity, chromatographic purity, phosphorus-related quality attributes, water sensitivity and performance in a short test sequence.
Product-family considerations
- Phosphoramidite chemistry is modular, automated and compatible with fast sequence iteration.
- Modified sugar, base or linker motifs let researchers tune duplex stability, specificity, hydrophobicity, steric profile and downstream conjugation options.
- Modified amidites can require adjusted coupling time, activator choice, deprotection conditions and analytical release methods.
- Moisture sensitivity and storage history are important because degraded amidite can reduce coupling efficiency.
- Silyl-protected RNA monomers require careful deprotection planning to protect product integrity.
Category literature
These publications provide background for the RNA (2'-O-TBDMS) Phosphoramidites product family. Individual product pages only show additional product- or feature-relevant references.
Selection checklist
| Exact identity | Match the canonical name with a CAS number, structure, SMILES or drawing; confirm stereochemistry, protecting groups and salt form where applicable. |
|---|---|
| Specification | Define target purity, analytical method, water or residual-solvent concerns and any application-specific acceptance limits. |
| Workflow fit | Share the reaction, enzyme, sequence, solvent system, support or analytical method used to evaluate compatibility. |
| Supply need | Provide initial quantity, expected future scale, packaging preference, timeline and documentation requirements. |
19 products
≥98% · CAS: N/A
BX-R2OT-0001DMTr-2'-O-TBDMS-2-S-rU-3'-CE-Phosphoramidite≥98% · CAS: N/A
BX-R2OT-0002DMTr-2'-O-TBDMS-5-Cl-rU-3'-CE-Phosphoramidite≥98% · CAS: N/A
BX-R2OT-0003DMTr-2'-O-TBDMS-5-F-rU-3'-CE-Phosphoramidite≥98% · CAS: 173241-78-6
BX-R2OT-0004DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite≥98% · CAS: 771494-03-2
BX-R2OT-0005DMTr-2'-O-TBDMS-N6-Me-N6-phenoxyacetyl-rA-3'-CE-Phosphoramidite≥98% · CAS: N/A
BX-R2OT-0006DMTr-2'-O-TBDMS-rA(Bz)-3'-(D)-PSM-Phosphoramidite≥98% · CAS: N/A
BX-R2OT-0007DMTr-2'-O-TBDMS-rA(Bz)-3'-(L)-PSM-Phosphoramidite≥98% · CAS: N/A
BX-R2OT-0008DMTr-2'-O-TBDMS-rG(dmf)-3'-CE-Phosphoramidite≥98% · CAS: 149559-87-5
BX-R2OT-00092'-O-TBDMS-rI PhosphoramiditeSpecification on request · CAS: 261518-12-1
BX-R2OT-0016DMTr-2'-O-TBDMS-5-OMe-rU-3'-CE-PhosphoramiditeSpecification on request · CAS: N/A
BX-R2OT-0017DMTr-2'-O-TBDMS-rC(Bz)-3'-CE-PhosphoramiditeSpecification on request · CAS: 118380-84-0
BX-R2OT-0018DMTr-2'-O-TBDMS-N6-Me-rA-3'-CE-PhosphoramiditeSpecification on request · CAS: 588698-79-7
BX-R2OT-0019DMTr-2'-O-TBDMS-N1-Me-pseudoU-3'-CE-PhosphoramiditeSpecification on request · CAS: 875302-45-7
BX-R2OT-0020DMTr-2'-O-TBDMS-pseudoU-3'-CE-PhosphoramiditeSpecification on request · CAS: 163496-23-9
BX-R2OT-0021DMTr-2'-O-TBDMS-rU-3'-CE-PhosphoramiditeSpecification on request · CAS: 118362-03-1
BX-R2OT-0022DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-PhosphoramiditeSpecification on request · CAS: 104992-55-4
BX-R2OT-0023DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-PhosphoramiditeSpecification on request · CAS: 147201-04-5
BX-R2OT-0024DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-PhosphoramiditeSpecification on request · CAS: 121058-88-6
BX-R2OT-0025Frequently asked questions
What are typical uses for RNA (2'-O-TBDMS) Phosphoramidites?
RNA (2'-O-TBDMS) Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.
What should be confirmed before ordering RNA (2'-O-TBDMS) Phosphoramidites?
Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.
Are custom quantities or related analogs available?
BX Lab reviews custom package sizes, catalog-adjacent analogs and research-use custom synthesis requests against the target structure, purity, scale and timeline.
Need help selecting a product?
Tell our scientists about your target chemistry, workflow, required purity and scale. We can help identify a catalog product, related analog or custom route.