GalNAc
GalNAc-NAG-37 Phosphoramidite
Quick view. We supply GalNAc-NAG-37 Phosphoramidite as a triantennary GalNAc phosphoramidite for synthesizing GalNAc-conjugated oligonucleotides. CAS 2199491-27-3. Catalog target purity: ≥95%.
Product profile
GalNAc-NAG-37 Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C80H127N10O37P; molecular weight 1851.88).
GalNAc-NAG-37 Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For GalNAc-NAG-37 Phosphoramidite, in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Confirmed or normalized name variants
- NAG 37
- NAG37 Phosphoramidite
- GalNAc-NAG 37
- BX-GALN-0022
Useful catalog search terms
- CAS 2199491-27-3
- Protected oligonucleotide phosphoramidite building block
- GalNAc ligand motif
- phosphoramidite coupling group
- GalNAc ligand, linker or conjugation intermediate
- GalNAc
Physicochemical data
| Key chemistry motifs | GalNAc ligand motif; phosphoramidite coupling group |
|---|---|
| Boiling point | 1541.0±65.0 °C(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe GalNAc-NAG-37 Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
(6R)-FR054
GalNAc · CAS: 10378-06-0
BX-GALN-0002AdemA-GalNAc Phosphoramidite
GalNAc · CAS: 1953147-02-8
BX-GALN-0003AdemC-GalNAc Phosphoramidite
GalNAc · CAS: N/A
BX-GALN-0004GalNAc PEG Cluster Phosphoramidite
GalNAc · CAS: N/A
BX-GALN-0005GalNAc-L96 Linker-Acid
GalNAc · CAS: 1426159-34-3
BX-GALN-0006GalNAc-L96 Linker-Azide
GalNAc · CAS: 2135330-72-0
Frequently asked questions
Can the package size for GalNAc-NAG-37 Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GALN-0008 and CAS 2199491-27-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss GalNAc-NAG-37 Phosphoramidite or the named structural feature represented by this product.