Modified Nucleosides
iso-Guanosine
Quick view. We supply iso-Guanosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 1818-71-9. Catalog target purity: Specification on request.
Product profile
iso-Guanosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H13N5O5; molecular weight 283.24).
iso-Guanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For iso-Guanosine, reported solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. Storage: -20°C.
Names and search terms
Confirmed or normalized name variants
- iso-Gr
- NSC 12161
- CROTONOSID
- CROTONOSIDE
- ISOGUANOSINE(P)
- 2-Hydroxydenosine
- isoguanineriboside
- 2-HYDROXYADENOSINE
Useful catalog search terms
- CAS 1818-71-9
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | 1S/C10H13N5O5/c11-7-4-8(14-10(19)13-7)15(2-12-4)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s |
|---|---|
| InChIKey | MIKUYHXYGGJMLM-UUOKFMHZSA-N |
| SMILES | NC1=NC(NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)=O |
| Melting point | 237-241 °C(Solv: water (7732-18-5)) |
| Density | 2.25±0.1 g/cm3(Predicted) |
| pKa | 8.25±0.40(Predicted) |
| Form | powder |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for iso-Guanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0296 and CAS 1818-71-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.