Modified Nucleosides
N3-Methyluridine
Quick view. We supply N3-Methyluridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 2140-69-4. Catalog target purity: Specification on request.
Product profile
N3-Methyluridine is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N2O6; molecular weight 258.23).
N3-Methyluridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For N3-Methyluridine, reported solubility: DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly, Sonicated). Storage: Store at -20°C.
Names and search terms
Confirmed or normalized name variants
- 3-methyluridine
- Nsc 246077
- Uridine, 3-methyl-
- Uridine, 3-methyl- (8ci)(9ci)
Useful catalog search terms
- CAS 2140-69-4
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H14N2O6/c1-11-6(14)2-3-12(10(11)17)9-8(16)7(15)5(4-13)18-9/h2-3,5,7-9,13,15-16H,4H2,1H3/t5-,7-,8-,9-/m1/s |
|---|---|
| InChIKey | UTQUILVPBZEHTK-ZOQUXTDFSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C=CC(=O)N(C)C2=O)[C@H](O)[C@@H]1O |
| Melting point | 108-110 °C |
| Boiling point | 501.1±60.0 °C(Predicted) |
| Density | 1.605±0.06 g/cm3(Predicted) |
| pKa | 13.26±0.70(Predicted) |
| Form | Solid |
| Color | White to Off-White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for N3-Methyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0375 and CAS 2140-69-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.