Amino-modified Nucleosides
N6-Aminoadenosine
Quick view. We supply N6-Aminoadenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 5746-27-0. Catalog target purity: Specification on request.
Product profile
N6-Aminoadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N6O4; molecular weight 282.26 g/mol (calculated from molecular formula)).
N6-Aminoadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For N6-Aminoadenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 6-Hydrazinyl-9-pentofuranosyl-9H-purine
Useful catalog search terms
- CAS 5746-27-0
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C10H14N6O4/c11-15-8-5-9(13-2-12-8)16(3-14-5)10-7(19)6(18)4(1-17)20-10/h2-4,6-7,10,17-19H,1,11H2,(H,12,13,15) |
| InChIKey | DGKZTAGCCXJUAT-UHFFFAOYSA-N |
| SMILES | NNc1ncnc2c1ncn2C1OC(CO)C(O)C1O |
| Boiling point | 761.6±70.0 °C(Predicted) |
| Density | 2.12±0.1 g/cm3(Predicted) |
| pKa | 13.21±0.70(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe N6-Aminoadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N6-Aminoadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0097 and CAS 5746-27-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.