GalNAc
Peracetylated GalNAc-L96-Amine
Quick view. We supply Peracetylated GalNAc-L96-Amine as an amine-functional tri-GalNAc L96 intermediate for coupling to acids, activated esters and linker scaffolds. CAS 1159408-65-7. Catalog target purity: ≥98%.
Product profile
Peracetylated GalNAc-L96-Amine is classified as galnac ligand, linker or conjugation intermediate (Formula C81H129F3N10O38; molecular weight 1907.95).
Peracetylated GalNAc-L96-Amine can be evaluated in ligand, linker and conjugation-route development for oligonucleotide delivery research.
For Peracetylated GalNAc-L96-Amine, reported solubility: DMSO: Sparingly Soluble: 1-10 mg/ml Ethanol: Sparingly Soluble: 1-10 mg/mlPBS (pH 7.2): Soluble: =10 mg/ml. Storage: 2-8°C, sealed storage, away from moisture and light.
Names and search terms
Confirmed or normalized name variants
- Tri-GalNAc(OAc)3 TFA
- 6-Amino-11,17-dioxo-6-[[3-o..
- BX-GALN-0028
Useful catalog search terms
- CAS 1159408-65-7
- GalNAc ligand, linker or conjugation intermediate
- amine functionality
- GalNAc ligand motif
- Tri-GalNAc(OAc)3 (TFA)
- GalNAc
Physicochemical data
| Key chemistry motifs | amine functionality; GalNAc ligand motif |
|---|---|
| Form | Oil |
| Color | White to off-white |
| InChIKey | ZQQFLUVDYMPTBZ-FCGQNKRGNA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Tri-GalNAc(OAc)3 TFA is a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. GalNAc-LYTAC engages the asialoglycoprotein receptor for targeted protein degradation. tri-GalNAc: triantenerrary N-acetylgalactosamine; LYTAC: lysosome-targeting chimera.
- Typical studies compare linker length, valency, attachment chemistry, purification strategy and analytical identity.
- The material may also support conjugate-reference or impurity-standard preparation.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe Peracetylated GalNAc-L96-Amine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for Peracetylated GalNAc-L96-Amine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GALN-0012 and CAS 1159408-65-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the GalNAc product family and its named chemistry.