Sugars
(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol
Quick view. We supply (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol as a protected or deoxygenated ribofuranose sugar building block for nucleoside and medicinal chemistry synthesis. CAS 263701-23-1. Catalog target purity: Specification on request.
Product profile
(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is classified as carbohydrate or ribofuranose building block (Formula C11 H12 F2 O4; molecular weight 246.21 g/mol (calculated from molecular formula)).
(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 1-deoxy-1-(2,4-difluorophenyl)-β-D-ribofuranose
- D-Ribitol, 1,4-anhydro-1-C-(2,4-difluorophenyl)-, (1S)-
Useful catalog search terms
- CAS 263701-23-1
- Carbohydrate or ribofuranose building block
- Sugars
Physicochemical data
| InChI | InChI=1S/C11H12F2O4/c12-5-1-2-6(7(13)3-5)11-10(16)9(15)8(4-14)17-11/h1-3,8-11,14-16H,4H2/t8-,9-,10-,11+/m1/s |
|---|---|
| InChIKey | PVOSUMDUOMMGTK-DBIOUOCHSA-N |
| SMILES | C1=CC(=C(C=C1F)F)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SUGA-0086 and CAS 263701-23-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
