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Other Modified Nucleosides

2',3'-Di-O-methyladenosine

Quick view. 2',3'-Di-O-methyladenosine is an adenosine derivative bearing methyl ethers at both the ribose 2'- and 3'-oxygen atoms for research-use modified-nucleoside chemistry. CAS 20649-46-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Chemical structure of 2',3'-Di-O-methyladenosine
Chemical structure
Catalog numberBX-MN-0158
CAS number20649-46-1
Purity≥98%
Pack sizeCustom packaging by inquiry

Product profile

Material identity

2',3'-Di-O-methyladenosine is classified as 2',3'-di-o-methyl ribonucleoside (Formula C12H17N5O4; molecular weight 295.29).

Typical application

2',3'-Di-O-methyladenosine — Doubly O-methylated adenosine for research-use modified-nucleoside chemistry.

Handling focus

For 2',3'-Di-O-methyladenosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

PubChem CID22880802
InChIKeyYLTDWADIGWTCSP-WOUKDFQISA-N
ModificationMethyl ethers at the ribose 2'- and 3'-oxygen atoms
InChIInChI=1S/C12H17N5O4/c1-19-8-6(3-18)21-12(9(8)20-2)17-5-16-7-10(13)14-4-15-11(7)17/h4-6,8-9,12,18H,3H2,1-2H3,(H2,13,14,15)/t6-,8-,9-,12-/m1/s1
SMILESCO[C@@H]1[C@H](O[C@H]([C@@H]1OC)N2C=NC3=C(N=CN=C32)N)CO

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

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Frequently asked questions

Can the package size for 2',3'-Di-O-methyladenosine be customized?

Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.

What information should be included in a quote request?

Quote catalog number BX-MN-0158 and CAS 20649-46-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.

Product-family literature

These publications provide peer-reviewed context for the Other Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.

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Technology platforms

Catalog-derived platform membership for navigating related chemistry and verifiable product sets.