Nucleosides & Deoxynucleosides
2'-dT
Quick view. 2'-dT (thymidine) is a canonical DNA nucleoside used in nucleotide synthesis, antiviral/nucleoside analog research and analytical standards. CAS 50-89-5. Catalog target purity: ≥99%.
Product profile
2'-dT is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N2O5; molecular weight 242.23).
2'-dT can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-dT, reported solubility: Acetone, DMSO (Slightly), Ethanol, Ethyl Acetate, Methanol (Slightly, Heated), P. Storage: 0-6°C.
Names and search terms
Confirmed or normalized name variants
- 1-(2-DEOXY-BETA-D-ERYTHRO-PENTOFURANOSYL)-5-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE
- 1-[2-DEOXY-BETA-D-RIBOFURANOSYL]-5-METHYLURACIL
- 1-[2-DEOXY-BETA-D-RIBOFURANOSYL]-5-METHYLURACYL
- 1-(2-DEOXY-BETA-D-RIBOFURANOSYL)THYMINE
- 1-[(2R,4S,5R)-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5-METHYL-PYRIMIDINE-2,4-DIONE
- 2,4(1H,3H)-PYRIMIDINEDIONE, 1-(2-DEOXY-BETA-D-ERYTHRO-PENTOFURANOSYL)-5-METHYL-
- 2'-DEOXYRIBOSYLTHYMINE
- 2'-DEOXYTHYMIDINE
Useful catalog search terms
- CAS 50-89-5
- Nucleoside or protected nucleoside intermediate
- Nucleosides & Deoxynucleosides
Physicochemical data
| Melting point | 186-188 °C(lit.) |
|---|---|
| Boiling point | 385.05°C (rough estimate) |
| Density | 1.3129 (rough estimate) |
| pKa | pK1:9.79;pK2:12.85 (25°C) |
| Form | Crystalline Powder |
| Color | White to almost white |
| SMILES | CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O |
| InChI | 1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s |
| InChIKey | IQFYYKKMVGJFEH-XLPZGREQSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
2'-dA
Nucleosides & Deoxynucleosides · CAS: 958-09-8
BX-NDO-00022'-dA·H₂O
Nucleosides & Deoxynucleosides · CAS: 16373-93-6
BX-NDO-00032'-dC
Nucleosides & Deoxynucleosides · CAS: 951-77-9
BX-NDO-00042'-dG
Nucleosides & Deoxynucleosides · CAS: 961-07-9
BX-NDO-00052'-dG·H₂O
Nucleosides & Deoxynucleosides · CAS: 312693-72-4
BX-NDO-00072'-dU
Nucleosides & Deoxynucleosides · CAS: 951-78-0
Frequently asked questions
Can the package size for 2'-dT be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-NDO-0006 and CAS 50-89-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Nucleosides & Deoxynucleosides product family and its named chemistry.