Intermediates
2'-F-m7GDP TEA Salt
Quick view. We supply 2'-F-m7GDP TEA Salt as a fluorinated methylguanosine diphosphate intermediate for cap analog exploration. It is used to evaluate 2'-fluoro substitution in cap-recognition, enzymatic capping and stability studies. CAS 956473-23-7. Catalog target purity: ≥95%.
Product profile
2'-F-m7GDP TEA Salt is classified as rna cap analog or cap-related nucleotide.
2'-F-m7GDP TEA Salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 2'-F-m7GDP TEA Salt, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- CAS 956473-23-7
- RNA cap analog or cap-related nucleotide
- 2'-fluoro modification
- Intermediates
Physicochemical data
| Key chemistry motifs | 2'-fluoro modification |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe 2'-F-m7GDP TEA Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-F-m7GDP TEA Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-INTE-0012 and CAS 956473-23-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Intermediates product family and its named chemistry.