Succinates
5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate, triethylammonium salt
Quick view. A protected 2'-O-MOE adenosine 3'-O-succinate represented as the triethylammonium salt, with 5'-O-DMT and N6-benzoyl protection. CAS 444814-78-2. Catalog target purity: ≥98%. Availability: Inquiry only; contact BX Lab to confirm current availability.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate, triethylammonium salt is classified as succinates.
5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate, triethylammonium salt is relevant to high-stability antisense oligonucleotide gapmer and affinity-tuning research.
For 5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate, triethylammonium salt, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- 2'-MOE-A(Bz) 3'-succinate, triethylammonium salt
Useful catalog search terms
- 5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate triethylammonium salt
- 2'-MOE-A(Bz) 3'-succinate
- CAS 444814-78-2
Physicochemical data
| Salt form | Triethylammonium salt |
|---|---|
| Salt molecular formula | C51H60N6O11 |
| Salt molecular weight | 933.07 |
| Free-acid component formula | C45H45N5O11 |
| Free-acid component molecular weight | 831.9 |
| Protection pattern | 5'-O-DMT; N6-benzoyl; 2'-O-MOE; 3'-O-succinate |
| Ribose stereochemistry | (2R,3R,4R,5R) in the PubChem free-acid representation |
| CAS indexing note | PubChem represents CAS 444814-78-2 as the free-acid component |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate, triethylammonium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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BX-SUCC-0004DMTr-2'-F-dC(Ac)-3'-succinate, TEA salt
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Frequently asked questions
Can the package size for 5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate, triethylammonium salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SUCC-0012 and CAS 444814-78-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Succinates product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.