Succinates
5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate, triethylammonium salt
Quick view. A protected 2'-O-MOE adenosine 3'-O-succinate represented as the triethylammonium salt, with 5'-O-DMT and N6-benzoyl protection. CAS 444814-78-2. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Structure
Structure form boundary. The displayed drawing omits catalog counterions and does not establish the complete supplied form, counterion stoichiometry or hydration state.
Identity of the displayed counterion-free structure
Scope. These values describe only the counterion-free structure shown above. They do not identify the complete catalog salt or establish counterion stoichiometry.
| Depicted identity | 5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate free acid |
|---|---|
| Depicted form | Counterion-free structure |
| Source database | PubChem |
| PubChem CID | 168447036 |
| Molecular formula | C45H45N5O11 |
| Molecular weight | 831.9 g/mol |
| InChIKey | QDFWOVDXCRSHLI-NPHJKCPPSA-N |
Machine-readable identifiers for the displayed structure
| SMILES | COCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OC(=O)CCC(=O)O |
|---|---|
| InChI | InChI=1S/C45H45N5O11/c1-55-24-25-58-40-39(61-37(53)23-22-36(51)52)35(60-44(40)50-28-48-38-41(46-27-47-42(38)50)49-43(54)29-10-6-4-7-11-29)26-59-45(30-12-8-5-9-13-30,31-14-18-33(56-2)19-15-31)32-16-20-34(57-3)21-17-32/h4-21,27-28,35,39-40,44H,22-26H2,1-3H3,(H,51,52)(H,46,47,49,54)/t35-,39-,40-,44-/m1/s1 |
Form boundary. The reviewed PubChem record establishes four assigned protected-ribose stereocentres for the free-acid component, not a complete counterion-inclusive salt structure.
Identifier context
These notes preserve the current catalog identifiers while making their review boundary explicit.
The listed InChIKey and structure image represent the reviewed parent/free-acid moiety. The triethylammonium counterion is not depicted; confirm the exact supplied salt form with BX Lab.
Product profile
5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate, triethylammonium salt is classified as succinates.
5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate, triethylammonium salt is relevant to high-stability antisense oligonucleotide gapmer and affinity-tuning research.
For 5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate, triethylammonium salt, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- 2'-MOE-A(Bz) 3'-succinate, triethylammonium salt
Useful catalog search terms
- 5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate triethylammonium salt
- 2'-MOE-A(Bz) 3'-succinate
- CAS 444814-78-2
Physicochemical data
| Salt form | Triethylammonium salt |
|---|---|
| Salt molecular formula | C51H60N6O11 |
| Salt molecular weight | 933.07 |
| Free-acid component formula | C45H45N5O11 |
| Free-acid component molecular weight | 831.90 |
| Protection pattern | 5'-O-DMT; N6-benzoyl; 2'-O-MOE; 3'-O-succinate |
| Ribose stereochemistry | (2R,3R,4R,5R) in the PubChem free-acid representation |
| CAS indexing note | PubChem represents CAS 444814-78-2 as the free-acid component |
| Structure representation | Parent/free-acid protected nucleoside-succinate moiety; triethylammonium counterion is not depicted |
| InChIKey review status | The listed InChIKey and structure image represent the reviewed parent/free-acid moiety. The triethylammonium counterion is not depicted; confirm the exact supplied salt form with BX Lab. |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate, triethylammonium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
5'-DMTr-2'-O-MOE-rG(iBu)-3'-succinate, TEA salt
Succinates · CAS: 2622236-65-9
BX-SUCC-0002Abasic Succinate
Succinates · CAS: 1428324-58-6
BX-SUCC-0003DMTr-2'-F-dA(Bz)-3'-succinate, TEA salt
Succinates · CAS: 2504147-10-6
BX-SUCC-0004DMTr-2'-F-dC(Ac)-3'-succinate, TEA salt
Succinates · CAS: N/A
BX-SUCC-0005DMTr-2'-F-dG(iBu)-3'-succinate, TEA salt
Succinates · CAS: 1241724-83-3
BX-SUCC-0006DMTr-2'-F-dU-3'-succinate, TEA salt
Succinates · CAS: 2294880-79-6
Frequently asked questions
Can the package size for 5'-O-DMT-N6-benzoyl-2'-O-MOE-adenosine-3'-O-succinate, triethylammonium salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SUCC-0012 and CAS 444814-78-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Succinates product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.