Other Phosphoramidites
2'-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3'-O-(4,4'-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine
Quick view. We supply 2'-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3'-O-(4,4'-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine as a hydrophobic or alkyl-modified phosphoramidite for installing lipophilic side chains into oligonucleotides. A public CAS number is not assigned for this exact form. Catalog target purity: Specification on request.
Structure confirmation
This item requires structure confirmation before quotation. Send the target structure, CAS number, SMILES, InChI or drawing for our technical review.
Canonical name plus a structure drawing, SMILES, InChI or unambiguous CAS number.
Protecting groups, stereochemistry, salt or counterion, hydration and requested form.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
2'-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3'-O-(4,4'-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine is classified as protected oligonucleotide phosphoramidite building block.
2'-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3'-O-(4,4'-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For 2'-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3'-O-(4,4'-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine, dye-labeled nucleotides or amidites are bulkier than native monomers; incorporation efficiency, label density, photobleaching and light exposure should be controlled.
Names and search terms
Useful catalog search terms
- Protected oligonucleotide phosphoramidite building block
- amine functionality
- fluorescent label
- phosphoramidite coupling group
- Other Phosphoramidites
Physicochemical data
| Key chemistry motifs | amine functionality; fluorescent label; phosphoramidite coupling group |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- Fluorescent labels enable non-radioactive detection and can reduce downstream staining or secondary-label steps.
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Dye-labeled nucleotides or amidites are bulkier than native monomers; incorporation efficiency, label density, photobleaching and light exposure should be controlled.
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2'-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3'-O-(4,4'-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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BX-OP-00066-((bis(4-methoxyphenyl)(phenyl)methyl)amino)hexyl (2-cyanoethyl) diisopropylphosphoramidite
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Frequently asked questions
Can the package size for 2'-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3'-O-(4,4'-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-OP-0154, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2'-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3'-O-(4,4'-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine or the named structural feature represented by this product.