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RNA (2'-O-TBDMS) Phosphoramidites

5'-O-DMTr-2'-O-TBDMS-inosine-3'-CE phosphoramidite

Quick view. A protected inosine phosphoramidite bearing 5'-O-DMTr and 2'-O-TBDMS groups for research-use RNA synthesis. CAS 261518-12-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Chemical structure of 5'-O-DMTr-2'-O-TBDMS-inosine-3'-CE phosphoramidite
Chemical structure
Catalog numberBX-R2OT-0016
CAS number261518-12-1
Purity≥98%
Pack sizeCustom packaging by inquiry

Product profile

Material identity

5'-O-DMTr-2'-O-TBDMS-inosine-3'-CE phosphoramidite is classified as rna (2'-o-tbdms) phosphoramidites (Formula C46H61N6O8PSi; molecular weight 885.07).

Typical application

5'-O-DMTr-2'-O-TBDMS-inosine-3'-CE phosphoramidite — Protected inosine building block for research-use RNA synthesis.

Handling focus

For 5'-O-DMTr-2'-O-TBDMS-inosine-3'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

PubChem CID135483567
NucleosideInosine
5' protectionDMTr
2'-O protectionTBDMS
3'-O group2-cyanoethyl N,N-diisopropyl phosphoramidite
InChIKeyZUFMOUFQBYZIHB-JFOZTMRSSA-N
InChIInChI=1S/C46H61N6O8PSi/c1-31(2)52(32(3)4)61(57-27-15-26-47)59-40-38(58-44(41(40)60-62(10,11)45(5,6)7)51-30-50-39-42(51)48-29-49-43(39)53)28-56-46(33-16-13-12-14-17-33,34-18-22-36(54-8)23-19-34)35-20-24-37(55-9)25-21-35/h12-14,16-25,29-32,38,40-41,44H,15,27-28H2,1-11H3,(H,48,49,53)/t38-,40-,41-,44-,61?/m1/s1
SMILESCOc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]cnc43)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Frequently asked questions

Can the package size for 5'-O-DMTr-2'-O-TBDMS-inosine-3'-CE phosphoramidite be customized?

Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.

What information should be included in a quote request?

Quote catalog number BX-R2OT-0016 and CAS 261518-12-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.

Product-family literature

These publications provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.

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Technology platforms

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