Succinates
DMTr-2'-OMe-U-3'-Succinate, TEA Salt
Quick view. DMTr-2'-OMe-U-3'-Succinate, TEA Salt is a protected 2'-O-methyluridine derivative bearing 5'-O-DMTr and a 3'-O-succinate group, with triethylamine explicitly represented. The reviewed identity corresponds to PubChem CID 138376012. CAS 1792211-00-7. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-OMe-U-3'-Succinate, TEA Salt is classified as protected 2'-o-methyluridine 3'-o-succinate triethylamine salt (Formula C41H51N3O11; molecular weight 761.90).
DMTr-2'-OMe-U-3'-Succinate, TEA Salt supports modified RNA/antisense designs where methylated ribose positions are used to improve stability or reduce unwanted immune stimulation.
For DMTr-2'-OMe-U-3'-Succinate, TEA Salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMTr-2'-O-methyluridine-3'-succinate, triethylamine salt
Useful catalog search terms
- CAS 1792211-00-7
- Succinates
Physicochemical data
| PubChem CID | 138376012 |
|---|---|
| InChIKey | NSOHGEALAZXRED-JLUFNGKWSA-N |
| Structural features | 5'-O-DMTr; 2'-O-methyl; uracil nucleobase; 3'-O-succinate; triethylamine component |
| InChI | InChI=1S/C35H36N2O11.C6H15N/c1-43-25-13-9-23(10-14-25)35(22-7-5-4-6-8-22,24-11-15-26(44-2)16-12-24)46-21-27-31(48-30(41)18-17-29(39)40)32(45-3)33(47-27)37-20-19-28(38)36-34(37)42;1-4-7(5-2)6-3/h4-16,19-20,27,31-33H,17-18,21H2,1-3H3,(H,39,40)(H,36,38,42);4-6H2,1-3H3/t27-,31-,32-,33-;/m1./s1 |
| SMILES | CCN(CC)CC.CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OC(=O)CCC(=O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe DMTr-2'-OMe-U-3'-Succinate, TEA Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-SUCC-0002Abasic Succinate
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BX-SUCC-0003DMTr-2'-F-dA(Bz)-3'-succinate, TEA salt
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BX-SUCC-0004DMTr-2'-F-dC(Ac)-3'-succinate, TEA salt
Succinates · CAS: N/A
BX-SUCC-0005DMTr-2'-F-dG(iBu)-3'-succinate, TEA salt
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BX-SUCC-0006DMTr-2'-F-dU-3'-succinate, TEA salt
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Frequently asked questions
Can the package size for DMTr-2'-OMe-U-3'-Succinate, TEA Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SUCC-0023 and CAS 1792211-00-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Succinates product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.