ddNTPs
3'-Azido-2',3'-dideoxy-dTTP Sodium Salt
Quick view. A 3'-azido-2',3'-dideoxy analog of thymidine triphosphate in sodium-salt form; molecular formula and weight are reported for the parent free acid. Parent/free-acid CAS 92586-35-1; this identifier does not represent the complete catalog product form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Structure
Structure form boundary. The displayed drawing omits catalog counterions and does not establish the complete supplied form, counterion stoichiometry or hydration state.
Identity of the displayed counterion-free structure
Scope. These values describe only the counterion-free structure shown above. They do not identify the complete catalog salt or establish counterion stoichiometry.
| Depicted identity | 3'-Azido-2',3'-dideoxythymidine triphosphate |
|---|---|
| Depicted form | Counterion-free structure |
| Source database | PubChem |
| PubChem CID | 72187 |
| Molecular formula | C10H16N5O13P3 |
| Molecular weight | 507.18 g/mol |
| InChIKey | GLWHPRRGGYLLRV-XLPZGREQSA-N |
Machine-readable identifiers for the displayed structure
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N=[N+]=[N-] |
|---|---|
| Connectivity SMILES | CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N=[N+]=[N-] |
| InChI | InChI=1S/C10H16N5O13P3/c1-5-3-15(10(17)12-9(5)16)8-2-6(13-14-11)7(26-8)4-25-30(21,22)28-31(23,24)27-29(18,19)20/h3,6-8H,2,4H2,1H3,(H,21,22)(H,23,24)(H,12,16,17)(H2,18,19,20)/t6-,7+,8+/m0/s1 |
Form boundary. The reviewed public records establish the displayed counterion-free parent identity. They do not establish sodium stoichiometry or the complete catalog salt form.
Identifier context
These notes preserve the current catalog identifiers while making their review boundary explicit.
Parent/free-acid CAS 92586-35-1 identifies the counterion-free parent only; it is not an unconditional identifier for the complete sodium-salt product. Confirm sodium stoichiometry and supplied form in the quote request.
Product profile
3'-Azido-2',3'-dideoxy-dTTP Sodium Salt is classified as ddntps.
3'-Azido-2',3'-dideoxy-dTTP Sodium Salt is useful as a bioorthogonal handle for post-synthetic conjugation to fluorophores, affinity tags, surfaces, peptides or other functional payloads.
For 3'-Azido-2',3'-dideoxy-dTTP Sodium Salt, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Confirmed or normalized name variants
- 3'-Azido-ddTTP
- 3'-Azido-2',3'-dideoxythymidine triphosphate
- Zidovudine triphosphate
Physicochemical data
| Parent/free-acid CAS | 92586-35-1 |
|---|---|
| CAS basis | Parent/free-acid identity only; not the complete catalog sodium-salt form |
| CAS publication scope | parent-free-acid-only |
| Free-acid molecular formula | C10H16N5O13P3 |
| Free-acid molecular weight | 507.18 |
| Sodium-salt identity status | Complete sodium-salt stoichiometry, formula and molecular weight pending exact-form source verification |
| Salt form | Sodium salt; sodium stoichiometry unspecified |
| Sugar stereochemistry | (2S,3S,5R) |
| Modification | 3'-azido-2',3'-dideoxy |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 3'-Azido-2',3'-dideoxy-dTTP Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-Amino-3'-deoxy-dATP Sodium Salt
ddNTPs · Parent/free-acid CAS: 90053-18-2
BX-DDNT-00023'-Amino-3'-deoxy-dCTP Sodium Salt
ddNTPs · CAS: 90053-17-1
BX-DDNT-00033'-Amino-3'-deoxy-dGTP Sodium Salt
ddNTPs · CAS: 90053-19-3
BX-DDNT-00043'-Amino-3'-deoxy-dTTP Sodium Salt
ddNTPs · Parent/free-acid CAS: 90053-16-0
BX-DDNT-00053'-Azido-2',3'-dideoxy-dATP Sodium Salt
ddNTPs · CAS: 92562-94-2
BX-DDNT-00063'-Azido-2',3'-dideoxy-dCTP Sodium Salt
ddNTPs · CAS: 92562-77-1
Frequently asked questions
Can the package size for 3'-Azido-2',3'-dideoxy-dTTP Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-DDNT-0008 and Parent/free-acid CAS 92586-35-1 (not a complete catalog-product CAS), the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.