Ara Nucleosides
4-Chloro-7-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
Quick view. A 2'-fluoro-beta-D-arabino pyrrolo[2,3-d]pyrimidine intermediate bearing a 4-chloro substituent for structure-specific nucleoside synthesis research. CAS 169516-60-3. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
![Chemical structure of 4-Chloro-7-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine](/structures/f63a7cf2d6544a65.svg)
Product profile
4-Chloro-7-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is classified as ara nucleosides (Formula C11H11ClFN3O3; molecular weight 287.67).
4-Chloro-7-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine — 2'-Fluoro-beta-D-arabino pyrrolo[2,3-d]pyrimidine intermediate for structure-specific nucleoside synthesis research.
For 4-Chloro-7-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- (2R,3R,4S,5R)-5-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
Useful catalog search terms
- CAS 169516-60-3
- fluoro arabino chloropyrrolopyrimidine
Physicochemical data
| Sugar configuration | 2'-Deoxy-2'-fluoro-beta-D-arabinofuranosyl |
|---|---|
| Hydroxyl state | Free 3' and 5' hydroxyls |
| Heterocycle | 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine |
| PubChem CID | 10446782 |
| InChI | InChI=1S/C11H11ClFN3O3/c12-9-5-1-2-16(10(5)15-4-14-9)11-7(13)8(18)6(3-17)19-11/h1-2,4,6-8,11,17-18H,3H2/t6-,7+,8-,11-/m1/s1 |
| InChIKey | XFKDBYKOIYHLSC-FBSDJGSXSA-N |
| SMILES | C1=CN(C2=C1C(=NC=N2)Cl)[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 4-Chloro-7-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 4-Chloro-7-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-ARN-0025 and CAS 169516-60-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Ara Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.