Bz-protected Nucleosides
4'-O-Ac-3'-O-Bz-2'-O-Me-N3-Bz-U
Quick view. Multiply protected uridine derivative bearing N3-benzoyl, 2'-O-methyl, 3'-O-benzoyl and 4'-O-acetyl substitution. CAS 2982811-94-7. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
4'-O-Ac-3'-O-Bz-2'-O-Me-N3-Bz-U is classified as bz-protected nucleosides (Formula C25H22N2O9).
4'-O-Ac-3'-O-Bz-2'-O-Me-N3-Bz-U supports modified RNA/antisense designs where methylated ribose positions are used to improve stability or reduce unwanted immune stimulation.
For 4'-O-Ac-3'-O-Bz-2'-O-Me-N3-Bz-U, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Useful catalog search terms
- 2982811-94-7
Physicochemical data
| Nucleoside | Uridine derivative |
|---|---|
| Nucleobase protection | N3-benzoyl |
| 2' substitution | O-methyl |
| 3' substitution | O-benzoyl |
| 4' substitution | O-acetyl; orientation unspecified in the reviewed structure |
| Calculated molecular weight | 494.46 g/mol |
| Connectivity SMILES | CC(=O)OC1C(C(C(O1)N2C=CC(=O)N(C2=O)C(=O)C3=CC=CC=C3)OC)OC(=O)C4=CC=CC=C4 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 4'-O-Ac-3'-O-Bz-2'-O-Me-N3-Bz-U or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
Frequently asked questions
Can the package size for 4'-O-Ac-3'-O-Bz-2'-O-Me-N3-Bz-U be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0025 and CAS 2982811-94-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Bz-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.