2'-FANA Nucleosides
5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine
Quick view. A beta-D-arabino cytidine nucleoside bearing fluorine at sugar C2' and bromine at nucleobase C5, identified by CAS 69123-93-9. CAS 69123-93-9. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine is classified as 2'-fana nucleosides (Formula C9H11BrFN3O4; molecular weight 324.10).
5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 2'-Fluoro-5-bromo-1-beta-D-arabinofuranosylcytosine
Useful catalog search terms
- CAS 69123-93-9
- PubChem CID 172392
Physicochemical data
| Sugar configuration | beta-D-arabino |
|---|---|
| Sugar modification | 2'-fluoro-2'-deoxy |
| Nucleobase modification | 5-bromo cytosine |
| InChIKey | DPTQLSGNVUCAMZ-BYPJNBLXSA-N |
| PubChem CID | 172392 |
| InChI | InChI=1S/C9H11BrFN3O4/c10-3-1-14(9(17)13-7(3)12)8-5(11)6(16)4(2-15)18-8/h1,4-6,8,15-16H,2H2,(H2,12,13,17)/t4-,5+,6-,8-/m1/s1 |
| SMILES | C1=C(C(=NC(=O)N1[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)F)N)Br |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FAN-0072 and CAS 69123-93-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.