5'(E)-VP Phosphoramidites
5'-POM-(E)-VP-2'-OMe-G(iBu)-3'-CE-Phosphoramidite
Quick view. 5'-POM-(E)-VP-2'-OMe-G(iBu)-3'-CE-Phosphoramidite is a POM-protected 5'-(E)-vinylphosphonate 2'-O-methyl guanosine building block for research-use oligonucleotide synthesis. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-POM-(E)-VP-2'-OMe-G(iBu)-3'-CE-Phosphoramidite is classified as pom-protected 5'-(e)-vinylphosphonate 2'-o-methyl n2-isobutyryl guanosine 3'-ce phosphoramidite (Formula C37H59N7O13P2; molecular weight 871.86).
5'-POM-(E)-VP-2'-OMe-G(iBu)-3'-CE-Phosphoramidite — POM-protected 5'-(E)-vinylphosphonate 2'-O-methyl guanosine phosphoramidite building block for research-use solid-phase oligonucleotide synthesis.
For 5'-POM-(E)-VP-2'-OMe-G(iBu)-3'-CE-Phosphoramidite, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 5'(E)-VP-2'-OMe-G(ibu) Phosphoramidite
- 5'(E)-VP-2'-OMe-iBu-G Phosphoramidite
- 5'-(E)-VPG Phosphoramidite
Useful catalog search terms
- HR-00226002
- C37H59N7O13P2
- 5'(E)-VP Phosphoramidites
Physicochemical data
| Appearance | White to off-white powder |
|---|---|
| Water | ≤0.5% |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 5'-POM-(E)-VP-2'-OMe-G(iBu)-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
Bis(POM)-(E)-5'-vinylphosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite
2'-O-Me Phosphoramidites · CAS: 2419895-65-9
BX-5EVP-00045'-POM-(E)-VP-2'-OMe-C(Bz)-3'-CE-Phosphoramidite
5'(E)-VP Phosphoramidites · CAS: N/A
BX-2OMP-00715'-POM-(E)-vinyl phosphonate-2'-O-Me-rU-3'-CE-Phosphoramidite
2'-O-Me Phosphoramidites · CAS: 2172373-55-4
Frequently asked questions
Can the package size for 5'-POM-(E)-VP-2'-OMe-G(iBu)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-5EVP-0003, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 5'(E)-VP Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.