Intermediates
5-Hydroxymethyl uracil
Quick view. We supply 5-Hydroxymethyl uracil as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 4433-40-3. Catalog target purity: Specification on request.
Product profile
5-Hydroxymethyl uracil is classified as specialty research-use chemical building block (Formula C5H6N2O3; molecular weight 142.11).
5-Hydroxymethyl uracil — 5-Hydroxymethyluracil (cas# 4433-40-3) is a compound useful in organic synthesis.
For 5-Hydroxymethyl uracil, reported solubility: DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly, Heated). Storage: Sealed in dry,Room Temperature.
Names and search terms
Confirmed or normalized name variants
- 2,4-DIHYDROXY-5-HYDROXYMETHYLPYRIMIDINE
- 5-(HYDROXYMETHYL)-2,4(1H,3H)PYRIMIDINEDIONE
- 5-(HYDROXYMETHYL)URACIL HYDRATE
- 5-HYDROXYMETHYLURACYL
- AURORA KA-547
- HYDROXYMETHYL URACIL
- RARECHEM AH CK 0115
- TIMTEC-BB SBB000084
Useful catalog search terms
- CAS 4433-40-3
- Specialty research-use chemical building block
- fluorescent label
- Intermediates
Physicochemical data
| Key chemistry motifs | fluorescent label |
|---|---|
| InChI | InChI=1S/C5H6N2O3/c8-2-3-1-6-5(10)7-4(3)9/h,8H,2H2,(H2,6,7,9,10) |
| InChIKey | JDBGXEHEIRGOBU-UHFFFAOYSA-N |
| SMILES | C1(=O)NC=C(CO)C(=O)N1 |
| Melting point | >300 °C(lit.) |
| Density | 1.401±0.06 g/cm3(Predicted) |
| pKa | 8.46±0.10(Predicted) |
| Form | Solid |
| Color | White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5-Hydroxymethyl uracil can be used as a defined research input for chemistry feasibility, analytical method development and material comparison.
- Typical qualification includes identity, purity method, storage, handling and downstream workflow compatibility.
- Related analogs, impurity standards and custom quantities can be reviewed for project-specific research needs.
Product-specific evaluation notes
Potential advantages
- Fluorescent labels enable non-radioactive detection and can reduce downstream staining or secondary-label steps.
Method limitations
- Dye-labeled nucleotides or amidites are bulkier than native monomers; incorporation efficiency, label density, photobleaching and light exposure should be controlled.
These points describe 5-Hydroxymethyl uracil or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-Hydroxymethyl uracil be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-INTE-0074 and CAS 4433-40-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 5-Hydroxymethyl uracil or the named structural feature represented by this product.