Protected Nucleosides
5'-O-DMTr-2'-O-TBDMS-rC(Ac)
Quick view. N4-acetyl-protected cytidine bearing a 5'-O-DMTr group, a 2'-O-TBDMS group and a free 3'-hydroxyl. CAS 121058-85-3. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Product profile
5'-O-DMTr-2'-O-TBDMS-rC(Ac) is classified as protected nucleosides (Formula C38H47N3O8Si; molecular weight 701.90 g/mol).
5'-O-DMTr-2'-O-TBDMS-rC(Ac) is supplied for research use within the Protected Nucleosides product family.
For 5'-O-DMTr-2'-O-TBDMS-rC(Ac), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- N4-Acetyl-5'-O-DMTr-2'-O-TBDMS-cytidine
- 5'-O-DMT-2'-O-TBDMS-N4-Ac-C
Useful catalog search terms
- PubChem CID 11136250
- CAS 121058-85-3
Physicochemical data
| PubChem CID | 11136250 |
|---|---|
| Nucleoside | Cytidine |
| Nucleobase protection | N4-acetyl |
| Hydroxyl protection | 5'-O-DMTr; 2'-O-TBDMS |
| Hydroxyl state | 3' hydroxyl group unprotected |
| InChI | InChI=1S/C38H47N3O8Si/c1-25(42)39-32-22-23-41(36(44)40-32)35-34(49-50(7,8)37(2,3)4)33(43)31(48-35)24-47-38(26-12-10-9-11-13-26,27-14-18-29(45-5)19-15-27)28-16-20-30(46-6)21-17-28/h9-23,31,33-35,43H,24H2,1-8H3,(H,39,40,42,44)/t31-,33-,34-,35-/m1/s1 |
| InChIKey | ZFRWPAYPCFTQHK-HYGOWAQNSA-N |
| SMILES | CC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)O[Si](C)(C)C(C)(C)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for 5'-O-DMTr-2'-O-TBDMS-rC(Ac) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0043 and CAS 121058-85-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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