ddNTPs
5-Propargylamino-ddCTP
Quick view. A C5-propargylamino-modified ddCTP parent compound for dye-nucleotide conjugation, labeling, and DNA-sequencing reagent research. CAS 114748-56-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Identifier context
These notes preserve the current catalog identifiers while making their review boundary explicit.
This CAS number is shared by multiple BX Lab catalog records. Confirm the exact salt, counterion, concentration and supplied form when requesting a quote.
Product profile
5-Propargylamino-ddCTP is classified as ddntps (Formula C12H19N4O12P3; molecular weight 504.22).
5-Propargylamino-ddCTP — Precursor research for cyanine dye-nucleotide conjugates
For 5-Propargylamino-ddCTP, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Confirmed or normalized name variants
- 5-PA-ddCTP
- 5-Propargylamino-2',3'-dideoxycytidine 5'-triphosphate
Useful catalog search terms
- 114748-56-0
Physicochemical data
| Modification | C5 propargylamino handle on 2',3'-dideoxycytidine triphosphate |
|---|---|
| Physical form | Solid; white to off-white |
| Storage temperature | -20 C; protect from direct light |
| Form note | Free form is prone to instability; the trisodium 25 mM solution is catalogued separately as BX-GSS-0010 |
| PubChem CID | 21779042 |
| InChIKey | UZTVDBNPCNJIGN-VHSXEESVSA-N |
| InChI | InChI=1S/C12H19N4O12P3/c13-5-1-2-8-6-16(12(17)15-11(8)14)10-4-3-9(26-10)7-25-30(21,22)28-31(23,24)27-29(18,19)20/h6,9-10H,3-5,7,13H2,(H,21,22)(H,23,24)(H2,14,15,17)(H2,18,19,20)/t9-,10+/m0/s1 |
| SMILES | NCC#Cc1cn([C@H]2CC[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)nc1N |
| CAS review status | This CAS number is shared by multiple BX Lab catalog records. Confirm the exact salt, counterion, concentration and supplied form when requesting a quote. |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Nucleic-acid labeling and DNA-sequencing reagent research
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 5-Propargylamino-ddCTP or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-Amino-3'-deoxy-dATP Sodium Salt
ddNTPs · Parent/free-acid CAS: 90053-18-2
BX-DDNT-00023'-Amino-3'-deoxy-dCTP Sodium Salt
ddNTPs · CAS: 90053-17-1
BX-DDNT-00033'-Amino-3'-deoxy-dGTP Sodium Salt
ddNTPs · CAS: 90053-19-3
BX-DDNT-00043'-Amino-3'-deoxy-dTTP Sodium Salt
ddNTPs · Parent/free-acid CAS: 90053-16-0
BX-DDNT-00053'-Azido-2',3'-dideoxy-dATP Sodium Salt
ddNTPs · CAS: 92562-94-2
BX-DDNT-00063'-Azido-2',3'-dideoxy-dCTP Sodium Salt
ddNTPs · CAS: 92562-77-1
Frequently asked questions
Can the package size for 5-Propargylamino-ddCTP be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GSS-0013 and CAS 114748-56-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.