ddNTPs
5-Propargylamino-ddUTP sodium salt
Quick view. A 100 mM aqueous sodium form of 5-propargylamino-ddUTP for chain-termination, dye-nucleotide conjugation, and sequencing-reagent research. Parent CAS 114748-59-3; this identifier does not represent the complete catalog product form. Catalog target purity: 98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Structure
Structure form boundary. The displayed drawing omits catalog counterions and does not establish the complete supplied form, counterion stoichiometry or hydration state.
Identity of the displayed counterion-free structure
Scope. These values describe only the counterion-free structure shown above. They do not identify the complete catalog salt or establish counterion stoichiometry.
| Depicted identity | 5-Propargylamino-ddUTP |
|---|---|
| Depicted form | Counterion-free structure |
| Source database | PubChem |
| PubChem CID | 11071202 |
| Molecular formula | C12H18N3O13P3 |
| Molecular weight | 505.20 g/mol |
| InChIKey | HOYCULDIPQRPFI-VHSXEESVSA-N |
Machine-readable identifiers for the displayed structure
| SMILES | C1C[C@@H](O[C@@H]1COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N2C=C(C(=O)NC2=O)C#CCN |
|---|---|
| InChI | InChI=1S/C12H18N3O13P3/c13-5-1-2-8-6-15(12(17)14-11(8)16)10-4-3-9(26-10)7-25-30(21,22)28-31(23,24)27-29(18,19)20/h6,9-10H,3-5,7,13H2,(H,21,22)(H,23,24)(H,14,16,17)(H2,18,19,20)/t9-,10+/m0/s1 |
Form boundary. The reviewed PubChem record establishes the counterion-free parent stereochemistry, not the complete catalog salt or counterion stoichiometry.
Identifier context
These notes preserve the current catalog identifiers while making their review boundary explicit.
This CAS number is shared by multiple BX Lab catalog records. Confirm the exact salt, counterion, concentration and supplied form when requesting a quote. Parent CAS 114748-59-3 identifies the counterion-free parent only; it is not an unconditional CAS identifier for the complete sodium product form.
Product profile
5-Propargylamino-ddUTP sodium salt is classified as ddntps.
5-Propargylamino-ddUTP sodium salt — Chain-termination and sequencing-reagent research
For 5-Propargylamino-ddUTP sodium salt, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Confirmed or normalized name variants
- 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate sodium salt
- 5-Propargylamino-ddUTP sodium
Useful catalog search terms
- 5-Propargylamino-ddUTP
Physicochemical data
| Parent CAS | 114748-59-3 |
|---|---|
| CAS basis | Parent identity only; not the complete catalog salt form |
| CAS publication scope | parent-only |
| Parent molecular formula | C12H18N3O13P3 |
| Parent molecular weight | 505.20 |
| Counterion | Sodium (fixed stoichiometry not published) |
| Solution concentration | 100 mM in water |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Dye-nucleotide conjugation and labeling research
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 5-Propargylamino-ddUTP sodium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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ddNTPs · CAS: 90053-17-1
BX-DDNT-00033'-Amino-3'-deoxy-dGTP Sodium Salt
ddNTPs · CAS: 90053-19-3
BX-DDNT-00043'-Amino-3'-deoxy-dTTP Sodium Salt
ddNTPs · Parent/free-acid CAS: 90053-16-0
BX-DDNT-00053'-Azido-2',3'-dideoxy-dATP Sodium Salt
ddNTPs · CAS: 92562-94-2
BX-DDNT-00063'-Azido-2',3'-dideoxy-dCTP Sodium Salt
ddNTPs · CAS: 92562-77-1
Frequently asked questions
Can the package size for 5-Propargylamino-ddUTP sodium salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GSS-0016 and Parent CAS 114748-59-3 (not a complete catalog-product CAS), the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.
